Evidence map›Paper›PMID 27459054›Full record

ArticleNature2016

Genomic insights into the origin of farming in the ancient Near East.

Iosif Lazaridis, Dani Nadel, Gary Rollefson, Deborah C Merrett, Nadin Rohland, Swapan Mallick, Daniel Fernandes, Mario Novak, Beatriz Gamarra, Kendra Sirak and 43 more

Abstract readHistorical Article
In one paragraph

Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 462 papers.

0numbers the graph read from it
0cells of the map it votes in
462citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

462 citing papers in PubMed.

  1. Ancient DNA and Human Physiology.Physiology (Bethesda, Md.) · 2026
    Review
  2. Article
  3. Appreciating diversity: a review of the Iranian genomic landscape.European journal of human genetics : EJHG · 2026
    Review
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  18. On the Edge of Empire: Paleogenomic Insights into Roman Dacia.bioRxiv : the preprint server for biology · 2026
    Article
  19. Article
  20. Article

402 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors.

Iosif Lazaridis
Dani Nadel
Gary Rollefson
Deborah C Merrett
Nadin Rohland
Swapan Mallick
Daniel Fernandes
Mario Novak
Beatriz Gamarra
Kendra Sirak
Sarah Connell
Kristin Stewardson
Eadaoin Harney
Qiaomei Fu
Gloria Gonzalez-Fortes
Eppie R Jones
Songül Alpaslan Roodenberg
György Lengyel
Fanny Bocquentin
Boris Gasparian
Janet M Monge
Michael Gregg
Vered Eshed
Ahuva-Sivan Mizrahi
Christopher Meiklejohn
Fokke Gerritsen
Luminita Bejenaru
Matthias Blüher
Archie Campbell
Gianpiero Cavalleri
David Comas
Philippe Froguel
Edmund Gilbert
Shona M Kerr
Peter Kovacs
Johannes Krause
Darren McGettigan
Michael Merrigan
D Andrew Merriwether
Seamus O'Reilly
Martin B Richards
Ornella Semino
Michel Shamoon-Pour
Gheorghe Stefanescu
Michael Stumvoll
Anke Tönjes
Antonio Torroni
James F Wilson
Loic Yengo
Nelli A Hovhannisyan
Nick Patterson
Ron Pinhasi
David Reich

Funding

Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
Chief Scientist Office CZD/16/6Chief Scientist Office CZD/16/6/4European Research Council 263441Howard Hughes Medical InstituteMedical Research Council MC_PC_U127561128NIGMS NIH HHS GM100233NIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000 and 1,400 bc, from Natufian hunter-gatherers to Bronze Age farmers. We show that the earliest populations of the Near East derived around half their ancestry from a 'Basal Eurasian' lineage that had little if any Neanderthal admixture and that separated from other non-African lineages before their separation from each other. The first farmers of the southern Levant (Israel and Jordan) and Zagros Mountains (Iran) were strongly genetically differentiated, and each descended from local hunter-gatherers. By the time of the Bronze Age, these two populations and Anatolian-related farmers had mixed with each other and with the hunter-gatherers of Europe to greatly reduce genetic differentiation. The impact of the Near Eastern farmers extended beyond the Near East: farmers related to those of Anatolia spread westward into Europe; farmers related to those of the Levant spread southward into East Africa; farmers related to those of Iran spread northward into the Eurasian steppe; and people related to both the early farmers of Iran and to the pastoralists of the Eurasian steppe spread eastward into South Asia.

Indexed as

GenomicsPhylogenyAfrica, EasternAgricultureAnimalsArmeniaAsiaDNAEuropeHistory, AncientHuman MigrationHumansHybridization, GeneticIranIsraelJordanDNA

Identifiers

PMID27459054
PMCPMC5003663

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.