ArticlePLoS biology2016
Caging and Uncaging Genetics.
Article in PLoS biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- CaAmerican journal of physiology. Cell physiology · 2020Article
- Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance.Trends in immunology · 2018Review
- Rapid environmental effects on gut nematode susceptibility in rewilded mice.PLoS biology · 2018Article
- Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies.G3 (Bethesda, Md.) · 2018Article
- Testing hypotheses for maternal effects in Daphnia magna.Journal of evolutionary biology · 2018Article
- Disease spread in age structured populations with maternal age effects.Ecology letters · 2017Article
- Bigger is better: changes in body size explain a maternal effect of food on offspring disease resistance.Ecology and evolution · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild? What is the best design for studying genetic variation? When should we consider it at all? The right experimental approach depends on what you want to know.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.