ArticleThe ISME journal2017
The antibiotic resistome of swine manure is significantly altered by association with the Musca domestica larvae gut microbiome.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 129 citations in OpenAlex.
- Black Soldier Fly Can Safely Co-Convert Antibiotic Fermentation Residue and Potato Peel Waste into a Valuable Feed Resource.Insects · 2026Article
- Unde venis? Bacterial resistance from environmental reservoirs to lettuce: tracking microbiome and resistome over a growth period.FEMS microbiology ecology · 2024Article
- Organic fertilization co-selects genetically linked antibiotic and metal(loid) resistance genes in global soil microbiome.Nature communications · 2024Article
- Housefly gut microbiomes as a reservoir and facilitator for the spread of antibiotic resistance.The ISME journal · 2024Article
- Resistome Study in Aquatic Environments.Journal of microbiology and biotechnology · 2023Review
- Beyond canonical models: why a broader understanding of Diptera-microbiota interactions is essential for vector-borne disease control.Evolutionary ecology · 2023Article
- Prevalence of macrolide-lincosamide-streptogramin resistant lactic acid bacteria isolated from food samples.Journal of food science and technology · 2023Article
- Alteration of Manure Antibiotic Resistance Genes via Soil Fauna Is Associated with the Intestinal Microbiome.mSystems · 2022Article
- Molecular Epidemiology of Antibiotic Resistance Genes and Virulence Factors in Multidrug-ResistantInternational journal of environmental research and public health · 2022Article
- Assessment of global health risk of antibiotic resistance genes.Nature communications · 2022Article
- Effects of Chinese medicine herbal residues on antibiotic resistance genes and the bacterial community in chicken manure composting.The Journal of antibiotics · 2022Article
- Influence of Dairy Cows Bedding Material on the Microbial Structure and Antibiotic Resistance Genes of Milk.Frontiers in microbiology · 2022Article
- Changes in the gut microbiota diversity of brown frogs (Rana dybowskii) after an antibiotic bath.BMC veterinary research · 2021Article
- Biochar and Hyperthermophiles as Additives Accelerate the Removal of Antibiotic Resistance Genes and Mobile Genetic Elements during Composting.Materials (Basel, Switzerland) · 2021Article
- Characteristics and nutrient function of intestinal bacterial communities in black soldier fly (Hermetia illucens L.) larvae in livestock manure conversion.Microbial biotechnology · 2021Article
- Manure-Based Amendments Influence Surface-Associated Bacteria and Markers of Antibiotic Resistance on Radishes Grown in Soils with Different Textures.Applied and environmental microbiology · 2021Article
- Insects, Rodents, and Pets as Reservoirs, Vectors, and Sentinels of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2021Review
- Black Soldier Fly (Hermetia illucens) Larvae Significantly Change the Microbial Community in Chicken Manure.Current microbiology · 2021Article
- Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae).Parasites & vectors · 2020Article
- Swine Manure Composting With Compound Microbial Inoculants: Removal of Antibiotic Resistance Genes and Their Associations With Microbial Community.Frontiers in microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The overuse of antibiotics as veterinary feed additives is potentially contributing to a significant reservoir of antibiotic resistance in agricultural farmlands via the application of antibiotic-contaminated manure. Vermicomposting of swine manure using housefly larvae is a promising biotechnology for waste reduction and control of antibiotic pollution. To determine how vermicomposting influences antibiotic resistance traits in swine manure, we explored the resistome and associated bacterial community dynamics during larvae gut transit over 6 days of treatment. In total, 94 out of 158 antibiotic resistance genes (ARGs) were significantly attenuated (by 85%), while 23 were significantly enriched (3.9-fold) following vermicomposting. The manure-borne bacterial community showed a decrease in the relative abundance of Bacteroidetes, and an increase in Proteobacteria, specifically Ignatzschineria, following gut transit. ARG attenuation was significantly correlated with changes in microbial community succession, especially reduction in Clostridiales and Bacteroidales. Six genomes were assembled from the manure, vermicompost (final product) and gut samples, including Pseudomonas, Providencia, Enterococcus, Bacteroides and Alcanivorax. Transposon-linked ARGs were more abundant in gut-associated bacteria compared with those from manure and vermicompost. Further, ARG-transposon gene cassettes had a high degree of synteny between metagenomic assemblies from gut and vermicompost samples, highlighting the significant contribution of gut microbiota through horizontal gene transfer to the resistome of vermicompost. In conclusion, the larvae gut microbiome significantly influences manure-borne community succession and the antibiotic resistome during animal manure processing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.