ArticleBrain and behavior2016
Epigenetic marks as the link between environment and development: examination of the associations between attachment, socioeconomic status, and methylation of the SLC6A4 gene.
Article in Brain and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
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- The ill fortune of attachment insecurity and dyadic distrust in marital satisfaction: a dyadic perspective in Turkish couples.BMC psychology · 2025Article
- Biocultural Aspects of Mental Distress: Expanding the Biomedical Model Towards an Integrative Biopsychosocial Understanding of Disorder.Integrative psychological & behavioral science · 2024Review
- A narrative on the neurobiological roots of attachment-system functioning.Communications psychology · 2024Review
- DNA methylation signatures as biomarkers of socioeconomic position.Environmental epigenetics · 2023Review
- Associations between indicators of socioeconomic position and DNA methylation: a scoping review.Clinical epigenetics · 2021Article
- Genetics of adult attachment: An updated review of the literature.World journal of psychiatry · 2021Review
- Epigenetics Underlying Susceptibility and Resilience Relating to Daily Life Stress, Work Stress, and Socioeconomic Status.Frontiers in psychiatry · 2020Review
- Autonomic nervous system functioning assessed during the Still-Face Paradigm: A meta-analysis and systematic review of methods, approach and findings.Developmental review : DR · 2018Article
- Borderline Personality Disorder in Adolescence as a Generalization of Disorganized Attachment.Frontiers in psychology · 2018Article
- From forensic epigenetics to forensic epigenomics: broadening DNA investigative intelligence.Genome biology · 2017Article
- Effects of pre- and postnatal maternal stress on infant temperament and autonomic nervous system reactivity and regulation in a diverse, low-income population.Development and psychopathology · 2017Article
- Epigenetic marks as the link between environment and development: examination of the associations between attachment, socioeconomic status, and methylation of the SLC6A4 gene.Brain and behavior · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpigenetic processes act as a link between environment and individual development. This pilot study examined the association between socioeconomic status (SES), attachment, and methylation of the promoter region of the serotonin transporter gene (SLC6A4).
methodsAttachment classification and SLC6A4 methylation was determined in 100 late adolescents. We hypothesized that (1) SES would interact with methylation to predict higher unresolved loss (UL) or trauma scores on the Adult Attachment Interview; (2) across SES, participants with unresolved attachment would have lower levels of methylation than organized or secure participants; and (3) within the unresolved classification, SES would predict methylation.
resultsResults showed that lower methylation and low-SES were associated with higher UL, and higher methylation and low-SES were associated with higher unresolved trauma. Across SES, unresolved participants had lower levels of methylation than organized participants. Within the unresolved category, low-SES unresolved participants had higher levels of methylation than mid/upper-SES participants. SES was unrelated to methylation within the secure and organized categories.
conclusionsThese results suggest that the quality of attachment relationships may impact epigenetic processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.