Evidence map›Paper›PMID 27458197›Full record

ReviewCirculation research2016

The Need for Speed: Mice, Men, and Myocardial Kinetic Reserve.

Paul M L Janssen, Brandon J Biesiadecki, Mark T Ziolo, Jonathan P Davis

Abstract readReview
In one paragraph

Review in Circulation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Large animal models of right heart failure due to pulmonary hypertension: a bridge to translational success.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Review
  3. Article
  4. PET imaging of cardiac sympathetic nervous system dysfunction using meta-[European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Assessing cerebral capillary function and stalling using single capillary reporters in ultrasound localization microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Hypergravity, Microgravity, and Animal Research.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  9. Review
  10. Review
  11. Article
  12. Pluripotent stem cell-based approaches for heart repair and the potential of genetic modifications.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Considerations and implications of currentFrontiers in cell and developmental biology · 2025
    Review
  18. CaCells · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul M L JanssenFrom the Department of Physiology and Cell Biology and D. Davis Heart Lung Research Institute, College of Medicine, The Ohio State University, Columbus. janssen.10@osu.edu.
Brandon J BiesiadeckiFrom the Department of Physiology and Cell Biology and D. Davis Heart Lung Research Institute, College of Medicine, The Ohio State University, Columbus.
Mark T ZioloFrom the Department of Physiology and Cell Biology and D. Davis Heart Lung Research Institute, College of Medicine, The Ohio State University, Columbus.
Jonathan P DavisFrom the Department of Physiology and Cell Biology and D. Davis Heart Lung Research Institute, College of Medicine, The Ohio State University, Columbus.

Funding

Frequency-dependent modulation of cardiac myofilament function in health/diseaseR01HL113084 · NHLBI · OHIO STATE UNIVERSITY · PI JANSSEN, PAULUS ML · 2012 to 2023
$4.6M
Integrated Crosstalk of Thin Filament Post-translational ModificationsR01HL114940 · NHLBI · OHIO STATE UNIVERSITY · PI BIESIADECKI, BRANDON J · 2013 to 2021
$3.6M
Mechanisms and synergies of therapeutic drug treatments in muscular dystrophyR01NS082868 · NINDS · OHIO STATE UNIVERSITY · PI JANSSEN, PAULUS ML, RAFAEL-FORTNEY, JILL A · 2013 to 2017
$1.7M
Electrical and mechanical behavior of live human myocardium in health and diseaseRC1HL099538 · NHLBI · OHIO STATE UNIVERSITY · PI JANSSEN, PAULUS ML · 2009 to 2010
$1.0M
Role of Cardiac Troponin in Health and DiseaseR56HL091986 · NHLBI · OHIO STATE UNIVERSITY · PI DAVIS, JONATHAN PAUL · 2015 to 2015
$379k
NHLBI NIH HHS R01 HL113084NHLBI NIH HHS R01 HL114940NHLBI NIH HHS R56 HL091986NHLBI NIH HHS RC1 HL099538NINDS NIH HHS R01 NS082868
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Models, AnimalAnimalsHeart RateHumansMiceMyocardial ContractionTime Factorscontractionheart failurehumanmouserelaxation

Identifiers

PMID27458197
PMCPMC4965177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.