Evidence map›Paper›PMID 27458041›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Agreement Between the Douleur Neuropathique in 4 Questions and Leeds Assessment of Neuropathic Symptoms and Signs Questionnaires to Classify Neuropathic Pain Among Patients with Leprosy.

Jamilly C V Santana, Victor S Santos, Ricardo Q Gurgel, Julianne C V Santana, Francisco P Reis, Luis E Cuevas, Vera L C Feitosa

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jamilly C V SantanaFederal University of Sergipe, Aracaju, Brazil.
Victor S SantosFederal University of Sergipe, Aracaju, Brazil. santosvictor19@gmail.com.
Ricardo Q GurgelFederal University of Sergipe, Aracaju, Brazil.
Julianne C V SantanaFederal University of Sergipe, Aracaju, Brazil.
Francisco P ReisTiradentes University, Aracaju, Brazil.
Luis E CuevasLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Vera L C FeitosaFederal University of Sergipe, Aracaju, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropathic pain (NP) often occurs during the course of leprosy, and screening tools to differentiate NP from non-NP are often used. However, their performance varies in different settings. The most frequently used scales are the Douleur Neuropathique in 4 questions (DN4) and the Leeds assessment of neuropathic symptoms and signs (LANSS) questionnaires. Thus, we conducted a study to evaluate the agreement between DN4 and LANSS questionnaires to classify NP in 195 leprosy patients attending two reference centers in Sergipe, Brazil. The DN4 and LANSS classified 166 and 110 patients, respectively, as having NP. One hundred and seven (54.8%) were classified as NP by both questionnaires; 59 (30.2%) solely by the DN4 questionnaire and three (1.5%) solely by the LANSS. The agreement of the questionnaires was 66.2% (weak agreement, Kappa = 0.30). Although both questionnaires identified a high proportion of NP, the development of more robust instruments is necessary to ensure the accuracy of diagnosis of leprosy patients classified as having NP.

Indexed as

AdultAgedBrazilCross-Sectional StudiesFemaleHumansLeprosyMaleMiddle AgedNeuralgiaReproducibility of ResultsSurveys and Questionnaires

Identifiers

PMID27458041
PMCPMC5062768

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.