ArticleScientific reports2016
Is ragweed pollen allergenicity governed by environmental conditions during plant growth and flowering?
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- A systematic review of the effects of temperature and precipitation on pollen concentrations and season timing, and implications for human health.International journal of biometeorology · 2021Pooled it
- Environmental drivers of the allergenic load caused by Ambrosia artemisiifolia pollen and its major allergen Amb a 1 in the atmosphere.International journal of biometeorology · 2025Article
- Biologic Pollution Due toInternational journal of environmental research and public health · 2022Article
- Plant Stress Scenarios Differentially Affect Expression and IgE Reactivity of Grass Group-1 Allergen (β-Expansin) in Maize and Rice Pollen.Frontiers in allergy · 2022Article
- High Phenotypic Plasticity in a Prominent Plant Invader along Altitudinal and Temperature Gradients.Plants (Basel, Switzerland) · 2021Article
- Year-to-year variation of the elemental and allergenic contents of Ailanthus altissima pollen grains: an allergomic study.Environmental monitoring and assessment · 2019Article
- Ambrosia artemisiifolia L. temperature-responsive traits influencing the prevalence and severity of pollinosis: a study in controlled conditions.BMC plant biology · 2019Article
- Direct effects of insecticides on common ragweed-implications for natural enemy exclusion trials.Journal of pesticide science · 2018Article
- Effect of Soil pH on the Growth, Reproductive Investment and Pollen Allergenicity ofFrontiers in plant science · 2018Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pollen allergenicity is one of the main factors influencing the prevalence and/or severity of allergic diseases. However, how genotype and environment contribute to ragweed pollen allergenicity has still to be established. To throw some light on the factors governing allergenicity, in this work 180 ragweed plants from three Regions (Canada, France, Italy) were grown in both controlled (constant) and standard environmental conditions (seasonal changes in temperature, relative humidity and light). Pollen from single plants was characterized for its allergenic potency and for the underlying regulation mechanisms by studying the qualitative and quantitative variations of the main isoforms of the major ragweed allergen Amb a 1. Results showed a statistically higher variability in allergenicity of pollen from standard conditions than from controlled conditions growing plants. This variability was due to differences among single plants, regardless of their origin, and was not ascribed to differences in the expression and IgE reactivity of individual Amb a 1 isoforms but rather to quantitative differences involving all the studied isoforms. It suggests that the allergenic potency of ragweed pollen and thus the severity of ragweed pollinosis mainly depends on environmental conditions during plant growth and flowering, which regulate the total Amb a 1 content.
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