Evidence map›Paper›PMID 27457689›Full record

ArticleBone2016

Ethnic differences in bone geometry between White, Black and South Asian men in the UK.

A Zengin, S R Pye, M J Cook, J E Adams, F C W Wu, T W O'Neill, K A Ward

Open access · hybridAbstract read
In one paragraph

Article in Bone, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. The association of coffee consumption with the risk of osteoporosis and fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
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  13. Patellar height measurement in Indonesian normal adult population.Annals of medicine and surgery (2012) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

A ZenginMedical Research Council Human Nutrition Research, Cambridge, UK. Electronic address: ayse.zengin@mrc-hnr.cam.ac.uk.
S R PyeArthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
M J CookArthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
J E AdamsRadiology and Manchester Academic Health Science Centre (MAHSC), Manchester Royal Infirmary, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester, Manchester, UK.
F C W WuAndrology Research Unit, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester, UK.
T W O'NeillArthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Department of Rheumatology, Salford Royal NHS Foundation Trust, Salford, UK.
K A WardMedical Research Council Human Nutrition Research, Cambridge, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK. Electronic address: kate.ward@mrc-hnr.cam.ac.uk.
Manchester Academic Health Science Centre · GBUniversity of Manchester · GBMedical Research Council · GBMRC Human Nutrition Research · GB

Funding

Arthritis Research UKMedical Research Council MC_U105960371
6 · The paper itself

Abstract

Relatively little is known about the bone health of ethnic groups within the UK and data are largely restricted to women. The aim of this study was to investigate ethnic differences in areal bone mineral density (aBMD), volumetric bone mineral density (vBMD), bone geometry and strength in UK men. White European, Black Afro-Caribbean and South Asian men aged over 40years were recruited from Greater Manchester, UK. aBMD at the spine, hip, femoral neck and whole body were measured by DXA. Bone geometry, strength and vBMD were measured at the radius and tibia using pQCT at the metaphysis (4%) and diaphysis (50% radius; 38% tibia) sites. Adjustments were made for age, weight and height. Black men had higher aBMD at the whole body, total hip and femoral neck compared to White and South Asian men independent of body size adjustments, with no differences between the latter two groups. White men had longer hip axis lengths than both Black and South Asian men. There were fewer differences in vBMD but White men had significantly lower cortical vBMD at the tibial diaphysis than Black and South Asian men (p<0.001). At the tibia and radius diaphysis, Black men had larger bones with thicker cortices and greater bending strength than the other groups. There were fewer differences between White and South Asian men. At the metaphysis, South Asian men had smaller bones (p=0.02) and lower trabecular vBMD at the tibia (p=0.003). At the diaphysis, after size-correction, South Asian men had similar sized bones but thinner cortices than White men; measures of strength were not broadly reduced in the South Asian men. Combining pQCT and DXA measurements has given insight into differences in bone phenotype in men from different ethnic backgrounds. Understanding such differences is important in understanding the aetiology of male osteoporosis.

Indexed as

Asian PeopleBlack PeopleEthnicityWhite PeopleAbsorptiometry, PhotonAdultAgedBone and BonesHumansMaleMiddle AgedTomography, X-Ray ComputedUnited KingdomAgingBoneDXAEthnicityGeometrypQCT

Identifiers

PMID27457689
PMCPMC5004623
OpenAlexW2479949210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.