ReviewGenes, brain, and behavior2017
Associative and sensorimotor cortico-basal ganglia circuit roles in effects of abused drugs.
Review in Genes, brain, and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 77 citations in OpenAlex.
- Impact of Voluntary Alcohol Consumption on Corticostriatal Plasticity in Rats.The European journal of neuroscience · 2026Article
- External Globus Pallidus Arkypallidal Circuit Dynamics Gate Risk-Taking Behavior.bioRxiv : the preprint server for biology · 2026Article
- Dissociable effects of LSD and MDMA on striato-cortical connectivity in healthy subjects.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Progressive Changes Between Thalamic Nuclei and Cortical Networks Across Stimulus-Response Learning.Human brain mapping · 2025Article
- Cortico-subcortical converging organization at rest.Scientific reports · 2025Article
- Alcohol effects on associative and sensorimotor cortico-thalamo-basal ganglia circuits alter decision making and alcohol intake.Alcohol (Fayetteville, N.Y.) · 2025Review
- Resting-State Sensory-Motor Connectivity between Hand and Mouth as a Neural Marker of Socioeconomic Disadvantage, Psychosocial Stress, Cognitive Difficulties, Impulsivity, Depression, and Substance Use in Children.Journal of cellular neuroscience · 2025Article
- Chronic alcohol induces subcircuit-specific striatonigral plasticity enhancing the sensorimotor basal ganglia role in action execution.Science advances · 2024Article
- Morphometric alterations of the mesocorticolimbic network in Parkinson's disease with impulse control disorders.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Multivariate and regional age-related change in basal ganglia iron in neonates.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Reconfigurations of Dynamic Functional Network Connectivity in Large-scale Brain Network after Prolonged Abstinence in Heroin Users.Current neuropharmacology · 2024Article
- The Effects of Digital Addiction on Brain Function and Structure of Children and Adolescents: A Scoping Review.Healthcare (Basel, Switzerland) · 2023Article
- Fluoxetine potentiates methylphenidate-induced behavioral responses: Enhanced locomotion or stereotypies and facilitated acquisition of cocaine self-administration.Addiction neuroscience · 2023Article
- Chronic alcohol exposure differentially alters calcium activity of striatal cell populations during actions.Addiction neuroscience · 2023Article
- Striatonigral direct pathway 2-arachidonoylglycerol contributes to ethanol effects on synaptic transmission and behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- The development of compulsive coping behavior depends on dorsolateral striatum dopamine-dependent mechanisms.Molecular psychiatry · 2023Article
- Chronic alcohol exposure alters action control via hyperactive premotor corticostriatal activity.Cell reports · 2023Article
- Bayesian network mediation analysis with application to the brain functional connectome.Statistics in medicine · 2022Article
- Effects of chronic alcohol exposure on motivation-based value updating.Alcohol (Fayetteville, N.Y.) · 2022Article
- Chronic Intermittent Ethanol Administration during Adolescence Produces Sex Dependent Impairments in Behavioral Flexibility and Survivability.Brain sciences · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The mammalian forebrain is characterized by the presence of several parallel cortico-basal ganglia circuits that shape the learning and control of actions. Among these are the associative, limbic and sensorimotor circuits. The function of all of these circuits has now been implicated in responses to drugs of abuse, as well as drug seeking and drug taking. While the limbic circuit has been most widely examined, key roles for the other two circuits in control of goal-directed and habitual instrumental actions related to drugs of abuse have been shown. In this review we describe the three circuits and effects of acute and chronic drug exposure on circuit physiology. Our main emphasis is on drug actions in dorsal striatal components of the associative and sensorimotor circuits. We then review key findings that have implicated these circuits in drug seeking and taking behaviors, as well as drug use disorders. Finally, we consider different models describing how the three cortico-basal ganglia circuits become involved in drug-related behaviors. This topic has implications for drug use disorders and addiction, as treatments that target the balance between the different circuits may be useful for reducing excessive substance use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.