ArticleInfection control and hospital epidemiology2016
Elimination of Routine Contact Precautions for Endemic Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus: A Retrospective Quasi-Experimental Study.
Article in Infection control and hospital epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Prevention in adults of transmission of infection with multidrug-resistant organisms: an updated systematic review from Making Healthcare Safer IV.BMJ quality & safety · 2025Pooled it
- Economic Evaluation of a Catheter-Associated Urinary Tract Infection Prevention Program in Nursing Homes.Journal of the American Geriatrics Society · 2018Trial
- Discontinuing contact precautions for COVID-19: the science says its time.Infection control and hospital epidemiology · 2026Article
- Greening Infection Prevention and Control: Multifaceted Approaches to a Sustainable Future.Open forum infectious diseases · 2025Article
- Implementation of contact precautions for multidrug-resistant organisms in the post-COVID-19 pandemic era: An updated national Emerging Infections Network (EIN) survey.Infection control and hospital epidemiology · 2024Article
- Ten sustainable steps infectious diseases professionals can take to mitigate the climate crisis.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Review
- Contact precautions for MRSA and VRE: where are we now? A survey of theAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Cessation of Rectal Screening for Vancomycin-Resistant Enterococci: Experience from a Tertiary Care Hospital from Türkiye.Healthcare (Basel, Switzerland) · 2023Article
- Considering the precautionary principle and its application to MRSA and SARS-CoV-2 as emerging novel pathogens of their time.Infection, disease & health · 2023Article
- Contact precautions for the control of endemic pathogens: Finding the middle path.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Perspectives and awareness of environmental sustainability in the infection prevention and control community nationally.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Association of Visitor Contact Precautions With Estimated Hospital-Onset Clostridioides difficile Infection Rates in Acute Care Hospitals.JAMA network open · 2021Article
- "Doc, I'm Going for a Walk": Liberalizing or Restricting the Movement of Hospitalized Patients-Ethical, Legal, and Clinical Considerations.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2020Article
- Comparison of surveillance and clinical cultures to measure the impact of infection control interventions on the incidence of methicillin-resistantInfection control and hospital epidemiology · 2020Article
- "Just Getting a Cup of Coffee"-Considering Best Practices for Patients' Movement off the Hospital Floor.Journal of hospital medicine · 2019Article
- Vancomycin-resistant enterococci (VRE): a reason to isolate?Infection · 2019Review
- Antibiotic stewardship and horizontal infection control are more effective than screening, isolation and eradication.Infection · 2018Review
- Noninfectious Hospital Adverse Events Decline After Elimination of Contact Precautions for MRSA and VRE.Infection control and hospital epidemiology · 2018Observational
- Regional Epidemiology of Methicillin-Resistant Staphylococcus aureus Among Adult Intensive Care Unit Patients Following State-Mandated Active Surveillance.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Long-Term Impact of Universal Contact Precautions on Rates of Multidrug-Resistant Organisms in ICUs: A Comparative Effectiveness Study.Infection control and hospital epidemiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
OBJECTIVE To evaluate the impact of discontinuation of contact precautions (CP) for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) and expansion of chlorhexidine gluconate (CHG) use on the health system. DESIGN Retrospective, nonrandomized, observational, quasi-experimental study. SETTING Two California hospitals. PARTICIPANTS Inpatients. METHODS We compared hospital-wide laboratory-identified clinical culture rates (as a marker of healthcare-associated infections) 1 year before and after routine CP for endemic MRSA and VRE were discontinued and CHG bathing was expanded to all units. Culture data from patients and cost data on material utilization were collected. Nursing time spent donning personal protective equipment was assessed and quantified using time-driven activity-based costing. RESULTS Average positive culture rates before and after discontinuing CP were 0.40 and 0.32 cultures/100 admissions for MRSA (P=.09), and 0.48 and 0.40 cultures/100 admissions for VRE (P=.14). When combining isolation gown and CHG costs, the health system saved $643,776 in 1 year. Before the change, 28.5% intensive care unit and 19% medicine/surgery beds were on CP for MRSA/VRE. On the basis of average room entries and donning time, estimated nursing time spent donning personal protective equipment for MRSA/VRE before the change was 45,277 hours/year (estimated cost, $4.6 million). CONCLUSION Discontinuing routine CP for endemic MRSA and VRE did not result in increased rates of MRSA or VRE after 1 year. With cost savings on materials, decreased healthcare worker time, and no concomitant increase in possible infections, elimination of routine CP may add substantial value to inpatient care delivery. Infect Control Hosp Epidemiol 2016;1-8.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.