Evidence map›Paper›PMID 27457238›Full record

ReviewCurrent diabetes reports2016

A Review of Insulin-Dosing Formulas for Continuous Subcutaneous Insulin Infusion (CSII) for Adults with Type 1 Diabetes.

Allen B King, Akio Kuroda, Munehide Matsuhisa, Todd Hobbs

Abstract readReview
In one paragraph

Review in Current diabetes reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  5. Insulin pumps in children - a systematic review.World journal of clinical pediatrics · 2022
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  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Allen B KingDiabetes Care Center, 1260 S. Main Street, Salinas, CA, 93901, USA. aking@diabetescarecenter.com.
Akio KurodaDiabetes Therapeutics and Research Center, Institute for Advanced Enzyme Research, Tokushima University, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Munehide MatsuhisaDiabetes Therapeutics and Research Center, Institute for Advanced Enzyme Research, Tokushima University, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Todd HobbsNovo Nordisk, Inc., 100 College Rd W, Princeton, NJ, 08540-6604, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dosing guidelines for patients with type 1 diabetes using continuous subcutaneous insulin infusion (CSII), which are historically based on clinical experience and retrospective studies of patients consuming an American diet, recommend that basal insulin should represent approximately 50 % of the total daily dose (TDD). Recent prospective studies in the USA and Japan conclude that the more appropriate proportion is closer to 30-40 % of TDD. In addition, currently used formulas for calculating the carbohydrate-to-insulin ratio (CIR) and correction factor (CF) may lead to underdosing of bolus insulin by as much as 12.8-50 % for a hypothetical patient. The discrepancies between traditional formulas and data from newer studies can be accounted for by the more rigorous design of the newer studies (e.g., prospective design, controlled diets, meal omission, and frequent glucose monitoring). International differences in diet composition may also be important to consider when developing dosing recommendations for CSII.

Indexed as

Infusions, SubcutaneousInsulin Infusion SystemsAdultDiabetes Mellitus, Type 1DietDose-Response Relationship, DrugHumansInsulinPractice Guidelines as TopicInsulinContinuous subcutaneous insulin infusionDosing formulasInsulin-dosing guidelinesInsulin pumpType 1 diabetes

Identifiers

PMID27457238
PMCPMC4960276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.