Evidence map›Paper›PMID 27457076›Full record

ArticleSurgical case reports2016

Gallbladder small cell carcinoma: a case report and literature review.

Toshiyuki Adachi, Masashi Haraguchi, Junji Irie, Tomoko Yoshimoto, Ryohei Uehara, Shinichiro Ito, Hirotaka Tokai, Kazumasa Noda, Nobuhiro Tada, Masataka Hirabaru and 3 more

Open access · goldAbstract read
In one paragraph

Article in Surgical case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. A Rare Case of Gallbladder Small Cell Carcinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  16. Article
  17. Observational
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Toshiyuki AdachiDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Masashi HaraguchiDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan. haraguci@mb.ejnet.ne.jp.
Junji IrieDepartment of Pathology, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Tomoko YoshimotoDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Ryohei UeharaDepartment of Internal Medicine, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Shinichiro ItoDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Hirotaka TokaiDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Kazumasa NodaDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Nobuhiro TadaDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Masataka HirabaruDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Keiji InoueDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Shigeki MinamiDepartment of Surgery, Nagasaki Harbor Medical Center City Hospital, Nagasaki, 850-8555, Japan.
Susumu EguchiDepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 852-8501, Japan.
Nagasaki Medical Center · JPNagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallbladder small cell carcinoma (SCC) comprises only 0.5 % of all gallbladder cancer and consists of aggressive tumors with poor survival outcomes against current treatments. These tumors are most common in elderly females, particularly those with cholecystolithiasis. We report the case of a 79-year-old woman with gallbladder small cell carcinoma. The patient had intermittent right upper quadrant abdominal pain and was admitted to our hospital due to suspected acute cholecystitis. She regularly received medical treatment for diabetes, hypertension, and dyslipidemia. On initial laboratory evaluation, the levels of aspartate aminotransferase (AST), total bilirubin, and C-reactive protein (CRP) were markedly elevated. She underwent computed tomography (CT) for screening. CT images showed a thick-walled gallbladder containing multiple stones and multiple 3-cm-sized round nodular lesions, which were suggestive of metastatic lymph nodes. After percutaneous transhepatic gallbladder drainage was performed, endoscopic ultrasound-guided fine needle aspiration of enlarged lymph nodes resulted in a diagnosis of small cell carcinoma or adenocarcinoma. However, we could not identify the primary lesion before the surgery because of no decisive factors. We performed cholecystectomy because there was a possibility of cholecystitis recurrence risk and also partial liver resection because we suspected tumor invasion. The final pathological diagnosis was neuroendocrine carcinoma of the gallbladder, small cell type. The tumor stage was IVb, T3aN1M1. The patient died 13 weeks after the surgery. In the present paper, we review the current available English-language literature of gallbladder SCC.

Indexed as

GallbladderNeuroendocrine tumorSmall cell carcinoma

Identifiers

PMID27457076
PMCPMC4960082
OpenAlexW2491119756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.