Evidence map›Paper›PMID 27456927›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2017

Changes in Utilization and Discard of Hepatitis C-Infected Donor Livers in the Recent Era.

M G Bowring, L M Kucirka, A B Massie, X Luo, A Cameron, M Sulkowski, K Rakestraw, A Gurakar, I Kuo, D L Segev and 1 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 105 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Viral hepatitis: Past, present, and future.World journal of gastroenterology · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. From hepatitis A to E: A critical review of viral hepatitis.World journal of gastroenterology · 2021
    Review
  11. Article
  12. Article
  13. Update on liver transplantation-newer aspectsTurkish journal of medical sciences · 2020
    Review
  14. Liver Transplant From Increased-Risk Donors in the Era of Direct-Acting Antivirals for Hepatitis C.Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation · 2020
    Article
  15. Article
  16. Liver transplant for hepatocellular carcinoma in the United States: Evolving trends over the last three decades.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  17. Review
  18. Hepatitis C-positive donor liver transplantation for hepatitis C seronegative recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2019
    Article
  19. Review
  20. Usage of HCV viremic organs in liver transplantation to anti-HCV negative recipients: The current status and review of literature.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

M G BowringDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
L M KucirkaDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
A B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
X LuoDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
A CameronDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
M SulkowskiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
K RakestrawDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
A GurakarDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
I KuoDepartment of Epidemiology and Biostatistics, George Washington University School of Public Health, Washington, DC.
D L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
C M DurandDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins Medicine · USJohns Hopkins University · USGeorge Washington University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007309 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 1985 to 2019
$43.2M
Patient Oriented Research in Hepatitis C-infected Injection Drug UsersK24DA034621 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SULKOWSKI, MARK SEBASTIAN · 2012 to 2022
$1.2M
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Optimal Antiretroviral Therapy During Bone Marrow Transplant in HIV-1 InfectionK23CA177321 · NCI · JOHNS HOPKINS UNIVERSITY · PI DURAND, CHRISTINE MARIE · 2014 to 2018
$808k
Understanding Mechanisms for Racial Disparities in Survival on DialysisF30DK095545 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KUCIRKA, LAUREN MARIE · 2012 to 2016
$239k
NCI NIH HHS K23 CA177321NIDA NIH HHS K24 DA034621NIDDK NIH HHS F30 DK095545NIDDK NIH HHS K24 DK101828NIGMS NIH HHS T32 GM007309
6 · The paper itself

Abstract

The impact of interferon (IFN)-free direct-acting antiviral (DAA) hepatitis C virus (HCV) treatments on utilization and outcomes associated with HCV-positive deceased donor liver transplantation (DDLT) is largely unknown. Using the Scientific Registry of Transplant Recipients, we identified 25 566 HCV-positive DDLT recipients from 2005 to 2015 and compared practices according to the introduction of DAA therapies using modified Poisson regression. The proportion of HCV-positive recipients who received HCV-positive livers increased from 6.9% in 2010 to 16.9% in 2015. HCV-positive recipients were 61% more likely to receive an HCV-positive liver after 2010 (early DAA/IFN era) (aRR:

Indexed as

Liver TransplantationTissue DonorsWaiting ListsAdolescentAdultAgedAntiviral AgentsFemaleFollow-Up StudiesGraft SurvivalHepacivirusHepatitis CHumansMaleMiddle AgedTissue and Organ ProcurementAntiviral Agentsclinical research/practicedonors and donation: deceasedinfection and infectious agentsinfectious diseaseliver transplantation/hepatologyviral: hepatitis C

Identifiers

PMID27456927
PMCPMC5266634
OpenAlexW2486792863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.