Evidence map›Paper›PMID 27456863›Full record

ArticleBMC nephrology2016

The Rivas Cohort Study: design and baseline characteristics of a Nicaraguan cohort.

Kailey Minnings, Madeline Fiore, Martha Mosco, Ryan Ferguson, Sarah Leatherman, Eric Kerns, James Kaufman, Melissa Fiore, Daniel Brooks, Juan Jose Amador and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Prevalence and Risk Factors for CKD in the General Population of Southwestern Nicaragua.Journal of the American Society of Nephrology : JASN · 2020
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Kailey MinningsUniversity of Toronto Faculty of Medicine, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.
Madeline FioreUMass Medical School, 55 N Lake Ave, Chestnut St. Apt 21, Worcester, MA 01604 34, UK.
Martha MoscoBeth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Ryan FergusonMassachusetts Veterans Epidemiology Research and Information Center Health, 150 South Huntington Avenue, Boston, MA, 02130, USA.
Sarah LeathermanVA Boston Healthcare System, 150 South Huntington Ave, Boston, MA, 02130, USA.
Eric KernsWarren Alpert Medical School of Brown University, 593 Eddy Street, APC 9, Providence, RI, 02903, USA.
James KaufmanVA New York Healthcare System, 423 East 23rd Street, New York, NY, 10010, USA.
Melissa FioreAthena Health, 311 Arsenal Street, Watertown, MA, 02472, USA.
Daniel BrooksBoston University School of Public Health, 715 Albany Street, T317E, Boston, MA, 02118, USA.
Juan Jose AmadorBoston University, 715 Albany St., Talbot 3 East, Boston, MA, 02118, USA.
Hillary PaulsenBoston Children's Hospital, 401 Park Dr., 6th Floor, Landmark Center, Boston, MA, 02115, USA.
Zachary ErnstbergerIndiana University School of Medicine, 340 West 10th Street, Suite 6200, Indianapolis, IN, 46202, USA.
Bricia TrejoBoston University School of Public Health, 801 Massachusetts Avenue 4th Floor, Boston, MA, 02118, USA.
Elyse SullivanNortheastern University, 350 Huntington Ave, Boston, MA, 02115, USA.
Amos LichtmanUMass Medical School, 55 N Lake Ave, Worcester, MA, 01604, USA.
Keriann NobilUniversity of Massachusetts Medical School, 55 N. Lake Ave, Worcester, MA, 01605, USA.
Matthew LawlorBoston University Schools of Medicine and Public Health, 72 E. Concord Street, Boston, MA, 02118, USA.
Cassandra ParkerBoston University Schools of Medicine and Public Health, 160 E Berkeley St. Apt 304, Boston, MA, 02118, USA.
Rulan ParekhHospital for Sick Children, University Health Network and University of Toronto, 555 University Ave, Toronto, ON, M5G1X8, Canada.
Louis FioreBoston University Schools of Medicine and Public Health, 72 E. Concord Street, Boston, MA, 02118, USA. lfiore@bu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA lack of advanced healthcare information systems and validated scientific cohorts in Nicaragua makes it difficult to estimate disease prevalences and other public health statistics. Although there is concern of an "epidemic" of chronic kidney disease (CKD) in this country, statistics regarding its magnitude are derived from only a small number of non-representative studies. Budgetary constraints and the logistical problems of maintaining a study cohort make longitudinal studies difficult. The Rivas Cohort was created to measure disease burden of CKD and other public health priorities in the Department of Rivas, Nicaragua. Using primarily volunteer research students and technologic innovation including GPS, digital photography and point of care biochemical analysis, the ability to establish a longitudinal chronic disease cohort is demonstrated.

methodsSubjects were recruited from consecutive adjacent households in thirty-two randomly selected communities in the ten municipalities that comprise the Department of Rivas in southern Pacific coastal Nicaragua. The study was conducted in two phases. In the first phase, subjects were enrolled into the cohort and consented for future re-contact. In Phase II, conducted two years later, attempts were made to re-contact 400 of these subjects for additional data collection. Demographic, lifestyle, occupational, exposure and health data was collected for both phases of the study. Blood and urine testing and height, weight and blood pressure measurements were also performed. GPS coordinates of homes were recorded and maps of remote communities created.

resultsOf 1397 adults living in 533 households approached for participation a total of 1242 (89 %) were enrolled in the cohort. The median age is 41 years and 43 % are male, demographics in agreement with Nicaraguan census data for the Department of Rivas. During Phase II we attempted to re-contact 400 subjects for a follow-up study of CKD. It was possible to re-contact 84 % of these participants and of those re-contacted 95 % agreed to participate in the follow-up study. Of subjects that were not successfully re-contacted the majority had either moved (32) or were not at home (22) at the time of the study team visits.

conclusionThe Rivas Cohort Study enrolled a representative sample of 1242 adults living in the Department of Rivas, Nicaragua. The high re-contact and participation rates at two years suggests that the cohort is suitable for long-term studies and presents opportunities for investigations of disease prevalence, incidence, treatment and other public health matters. GPS coordinates and maps are available for future researchers who wish to use the cohort for additional studies.

Indexed as

AdultCohort StudiesCreatinineDemographyFemaleFollow-Up StudiesGeographic Information SystemsHumansLongitudinal StudiesMaleNicaraguaPoint-of-Care SystemsPrevalenceRenal InsufficiencyUrinalysisCreatinineBaseline SurveyCentral AmericaCohort studiesCreatinineData collectionNicaraguaPublic healthPublic health surveillanceRenal insufficiency

Identifiers

PMID27456863
PMCPMC4959050

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.