ArticleBMC nephrology2016
Is HRQOL in dialysis associated with patient survival or graft function after kidney transplantation?
Article in BMC nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Associations among body composition parameters and quality of life in peritoneal dialysis patients.Scientific reports · 2022Observational
- Poor Physical Function Trajectory Predicts Impaired Patient Survival in Older Recipients of Deceased Donor Kidneys: A Prospective Cohort Study.Transplantation direct · 2022Article
- A Comorbidity Index and Pretransplant Physical Status Predict Survival in Older Kidney Transplant Recipients: A National Prospective Study.Transplantation direct · 2022Article
- Physical Function in Kidney Transplantation: Current Knowledge and Future Directions.Current transplantation reports · 2020Article
- Comparison of longitudinal quality of life outcomes in preemptive and dialyzed patients on waiting list for kidney transplantation.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review.PloS one · 2020Article
- Quality of life of individuals receiving kidney transplantation in Amazonas State.Revista latino-americana de enfermagem · 2020Article
- Modality transition on renal replacement therapy and quality of life of patients: a 10-year follow-up cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Increasing kidney donor profile index sequence does not adversely affect medium-term health-related quality of life after kidney transplantation.Clinical transplantation · 2018Article
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4 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth related quality of life (HRQOL) is patient-reported, and an important treatment outcome for patients undergoing renal replacement therapy. Whether HRQOL in dialysis can affect mortality or graft survival after renal transplantation (RTX) is not determined. The aims of the present study were to investigate whether pretransplant HRQOL is associated with post-RTX patient survival or graft function, and to assess whether improvement in HRQOL from dialysis to RTX is associated with patient survival.
methodsIn a longitudinal prospective study, HRQOL was measured in 142 prevalent dialysis patients (67 % males, mean age 51 ± 15.5 years) who subsequent underwent renal transplantation. HRQOL could be repeated in 110 transplant patients 41 (IQR 34-51) months after RTX using the self-administered Kidney Disease and Quality of Life Short Form (KDQOL-SF) measure. Kaplan-Meier plots were utilized for survival analyses, and linear regression models were used to address HRQOL and effect on graft function.
resultsFollow-up time was 102 (IQR 97-108) months after RTX. Survival after RTX was higher in patients who perceived good physical function (PF) in dialysis compared to patients with poorer PF (p = 0.019). Low scores in the domain mental health measured in dialysis was associated with accelerated decline in graft function (p = 0.048). Improvements in the kidney-specific domains "symptoms" and "effect of kidney disease" in the trajectory from dialysis to RTX were associated with a survival benefit (p = 0.007 and p = 0.02, respectively).
conclusionHRQOL measured in dialysis patients was associated with survival and graft function after RTX. These findings may be useful in clinical pretransplant evaluations. Improvements in some of the kidney-specific HRQOL domains from dialysis to RTX were associated with lower mortality. Prospective and interventional studies are warranted.
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