ArticleInternational journal of environmental research and public health2016
Efficacy of a Low Dose of Hydrogen Peroxide (Peroxy Ag⁺) for Continuous Treatment of Dental Unit Water Lines: Challenge Test with Legionella pneumophila Serogroup 1 in a Simulated Dental Unit Waterline.
Article in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Application of Silver to Decontaminate Dental Unit Waterlines-a Systematic Review.Biological trace element research · 2022Pooled it
- Biweekly versus triweekly hydrogen peroxide shock treatment for controlling dental unit waterline contamination: a single-center pilot randomized clinical study.Frontiers in oral health · 2026Article
- Periodic detection and disinfection maintenance of dental unit waterlines in dental simulation head model laboratories.Scientific reports · 2025Article
- Microbial contamination levels in water derived from dental units used in small animal dentistry.Frontiers in veterinary science · 2025Article
- Initial waterline contamination byMicrobiology spectrum · 2024Article
- Study on the disinfection effect of chlorine dioxide disinfectant (ClOBMC oral health · 2024Article
- Splatter generated by oral surgery irrigation and its implication for infection control.Clinical oral investigations · 2023Article
- Article
- Environmental Management ofMicroorganisms · 2021Review
- Efficacy of BRSInternational journal of environmental research and public health · 2020Article
- Water Contamination Risks at the Dental Clinic.Biology · 2020Article
- Article
- Advances inPathogens (Basel, Switzerland) · 2019Article
- Three key factors influencing the bacterial contamination of dental unit waterlines: a 6-year survey from 2012 to 2017.International dental journal · 2019Article
- Plasma Sterilization Effectively Reduces Bacterial Contamination in Dental Unit Waterlines.International journal of dentistry · 2019Article
- Application of Hydrogen Peroxide as an Innovative Method of Treatment for Legionella Control in a Hospital Water Network.Pathogens (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was designed to examine the in vitro bactericidal activity of hydrogen peroxide against Legionella. We tested hydrogen peroxide (Peroxy Ag⁺) at 600 ppm to evaluate Legionella survival in a simulated dental treatment water system equipped with Water Hygienization Equipment (W.H.E.) device that was artificially contaminated. When Legionella pneumophila serogroup (sg) 1 was exposed to Peroxy Ag⁺ for 60 min we obtained a two decimal log reduction. High antimicrobial efficacy was obtained with extended periods of exposure: four decimal log reduction at 75 min and five decimal log reduction at 15 h of exposure. Involving a simulation device (Peroxy Ag⁺ is flushed into the simulation dental unit waterlines (DUWL)) we obtained an average reduction of 85% of Legionella load. The product is effective in reducing the number of Legionella cells after 75 min of contact time (99.997%) in the simulator device under test conditions. The Peroxy Ag⁺ treatment is safe for continuous use in the dental water supply system (i.e., it is safe for patient contact), so it could be used as a preventive option, and it may be useful in long-term treatments, alone or coupled with a daily or periodic shock treatment.
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