ReviewMarine drugs2016
From Discovery to Production: Biotechnology of Marine Fungi for the Production of New Antibiotics.
Review in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed.
- Endophytic Fungi Associated with Seaweeds as Potential Producers of Antimicrobial Compounds.Marine biotechnology (New York, N.Y.) · 2026Article
- Investigating the distribution of antibiotic resistance genes in relation to bacterial, fungal, and functional diversity in a hay field.Microbiology spectrum · 2026Article
- Uncovering fungal diversity in mangroves: new records, ecological insights, and phylogenetic analysis of3 Biotech · 2025Article
- Analyzing the Challenges and Opportunities Associated With Harnessing New Antibiotics From the Fungal Microbiome.MicrobiologyOpen · 2025Review
- Marine fungal metabolites as antiviral agents: Computer-aided drug screening for selective inhibition of African swine fever virus dUTPase.BioImpacts : BI · 2025Article
- Marine Fungi Bioactives with Anti-Inflammatory, Antithrombotic and Antioxidant Health-Promoting Properties Against Inflammation-Related Chronic Diseases.Marine drugs · 2024Review
- Integrative workflows for the characterization of hydrophobin and cerato-platanin in the marine fungus Paradendryphiella salina.Archives of microbiology · 2024Article
- Diversity and characterization of culturable fungi associated with the marine sea cucumber Holothuria scabra.PloS one · 2024Article
- Microbially Influenced Corrosion of Steel in Marine Environments: A Review from Mechanisms to Prevention.Microorganisms · 2023Review
- Marine fungi: A treasure trove of novel natural products and for biological discovery.PLoS pathogens · 2023Article
- Marine Resources Offer New Compounds and Strategies for the Treatment of Skin and Soft Tissue Infections.Marine drugs · 2023Review
- Austalide derivative from marine-derivedRSC advances · 2023Article
- PeruNPDB: the Peruvian Natural Products Database for in silico drug screening.Scientific reports · 2023Article
- Article
- Diversity and Biosynthetic Potential of Fungi Isolated from St. John's Island, Singapore.International journal of molecular sciences · 2023Article
- New opportunities and challenges of natural products research: When target identification meets single-cell multiomics.Acta pharmaceutica Sinica. B · 2022Review
- Recent Advances in the Heterologous Expression of Biosynthetic Gene Clusters for Marine Natural Products.Marine drugs · 2022Review
- Diversity, Abundance, and Ecological Roles of Planktonic Fungi in Marine Environments.Journal of fungi (Basel, Switzerland) · 2022Review
- Carbapenem Resistance among Marine Bacteria-An Emerging Threat to the Global Health Sector.Microorganisms · 2021Review
- Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis.Communications chemistry · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Filamentous fungi are well known for their capability of producing antibiotic natural products. Recent studies have demonstrated the potential of antimicrobials with vast chemodiversity from marine fungi. Development of such natural products into lead compounds requires sustainable supply. Marine biotechnology can significantly contribute to the production of new antibiotics at various levels of the process chain including discovery, production, downstream processing, and lead development. However, the number of biotechnological processes described for large-scale production from marine fungi is far from the sum of the newly-discovered natural antibiotics. Methods and technologies applied in marine fungal biotechnology largely derive from analogous terrestrial processes and rarely reflect the specific demands of the marine fungi. The current developments in metabolic engineering and marine microbiology are not yet transferred into processes, but offer numerous options for improvement of production processes and establishment of new process chains. This review summarises the current state in biotechnological production of marine fungal antibiotics and points out the enormous potential of biotechnology in all stages of the discovery-to-development pipeline. At the same time, the literature survey reveals that more biotechnology transfer and method developments are needed for a sustainable and innovative production of marine fungal antibiotics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.