Evidence map›Paper›PMID 27455046›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2016

Heritability of Thoracic Spine Curvature and Genetic Correlations With Other Spine Traits: The Framingham Study.

Michelle S Yau, Serkalem Demissie, Yanhua Zhou, Dennis E Anderson, Amanda L Lorbergs, Douglas P Kiel, Brett T Allaire, Laiji Yang, L Adrienne Cupples, Thomas G Travison and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Association of vertebral fractures with worsening degenerative changes of the spine: a longitudinal study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Bone reports · 2022
    Article
  8. Article
  9. Article
  10. Factors Associated With Kyphosis and Kyphosis Progression in Older Men: The MrOS Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Article
  11. Article
  12. Review
  13. A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
  14. Prediction of incident vertebral fracture using CT-based finite element analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Comparison of spinal alignment, muscular strength, and quality of life between women with postmenopausal osteoporosis and healthy volunteers.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Michelle S YauInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Serkalem DemissieDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Yanhua ZhouDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Dennis E AndersonCenter for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Amanda L LorbergsInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Douglas P KielInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Brett T AllaireDepartment of Orthopedic Surgery, Harvard Medical School, Boston, MA, USA.
Laiji YangInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
L Adrienne CupplesDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Thomas G TravisonInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Mary L BouxseinCenter for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA.
David KarasikInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Elizabeth J SamelsonInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.
Beth Israel Deaconess Medical Center · USBoston University · USHarvard University · USHebrew SeniorLife · USOctapharma (United States) · USBar-Ilan University · ILNational Heart Lung and Blood Institute · US

Funding

Translational Researchin Aging Trainnig ProgramT32AG023480 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2004 to 2024
$7.6M
Mechansims and Clinical Importance of Hyperkyphosis:The Framingham StudyR01AG041658 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI SAMELSON, ELIZABETH J · 2011 to 2015
$2.6M
Volumetric Bone Density and Vascular Calcification: The Framingham QCT StudyK01AR053118 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI SAMELSON, ELIZABETH J · 2007 to 2011
$481k
NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INIAMS NIH HHS K01 AR053118NIA NIH HHS R01 AG041658NIA NIH HHS T32 AG023480
6 · The paper itself

Abstract

Hyperkyphosis is a common spinal disorder in older adults, characterized by excessive forward curvature of the thoracic spine and adverse health outcomes. The etiology of hyperkyphosis has not been firmly established, but may be related to changes that occur with aging in the vertebrae, discs, joints, and muscles, which function as a unit to support the spine. Determining the contribution of genetics to thoracic spine curvature and the degree of genetic sharing among co-occurring measures of spine health may provide insight into the etiology of hyperkyphosis. The purpose of our study was to estimate heritability of thoracic spine curvature using T

Indexed as

AgedAge DistributionAlgorithmsFemaleHumansInheritance PatternsKyphosisMaleMiddle AgedPhenotypeSpinal CurvaturesThoracic VertebraeTomography, X-Ray ComputedAGINGDISEASES AND DISORDERS RELATED TO BONEEPIDEMIOLOGYGENETIC RESEARCHQCT

Identifiers

PMID27455046
PMCPMC5282513
OpenAlexW2494983775

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.