Evidence map›Paper›PMID 27454737›Full record

ArticleNature biotechnology2016

Genetic improvement of tomato by targeted control of fruit softening.

Selman Uluisik, Natalie H Chapman, Rebecca Smith, Mervin Poole, Gary Adams, Richard B Gillis, Tabot M D Besong, Judith Sheldon, Suzy Stiegelmeyer, Laura Perez and 19 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Fine-mapping and candidate gene analysis of qFF3.1 conferring fruit firmness in a modern tomato variety.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Analysis of the Causes of Split Pit in Peaches.International journal of molecular sciences · 2025
    Review
  20. Article

76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Selman UluisikSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Natalie H ChapmanSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Rebecca SmithSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Mervin PooleHeygates Ltd, Bugbrooke Mills, Bugbrooke, UK.
Gary AdamsSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Richard B GillisSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Tabot M D BesongSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Judith SheldonSyngenta Seeds, Jealott's Hill International Research Station, Bracknell, UK.
Suzy StiegelmeyerSyngenta Crop Protection, Research Triangle Park, North Carolina, USA.
Laura PerezSchool of Biological Sciences, Royal Holloway University of London, Egham Hill, UK.
Nurul SamsulrizalSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Duoduo WangSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Ian D FiskSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.ORCID 0000-0001-8448-3123
Ni YangSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Charles BaxterSyngenta Seeds, Jealott's Hill International Research Station, Bracknell, UK.
Daniel RickettSyngenta Seeds, Jealott's Hill International Research Station, Bracknell, UK.
Rupert FraySchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Barbara Blanco-UlatePlant Sciences Department, University of California, Davis, California, USA.
Ann L T PowellPlant Sciences Department, University of California, Davis, California, USA.
Stephen E HardingSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Jim CraigonSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Jocelyn K C RosePlant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.
Eric A FichPlant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.
Li SunDepartment of Biology and Skidmore Microscopy Imaging Center, Skidmore College, Saratoga Springs, New York, USA.
David S DomozychDepartment of Biology and Skidmore Microscopy Imaging Center, Skidmore College, Saratoga Springs, New York, USA.
Paul D FraserSchool of Biological Sciences, Royal Holloway University of London, Egham Hill, UK.
Gregory A TuckerSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Don GriersonSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Graham B SeymourSchool of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.ORCID 0000-0001-8365-4947

Funding

Biotechnology and Biological Sciences Research Council BB/J015598/1Biotechnology and Biological Sciences Research Council BB/J016071/1
6 · The paper itself

Abstract

Controlling the rate of softening to extend shelf life was a key target for researchers engineering genetically modified (GM) tomatoes in the 1990s, but only modest improvements were achieved. Hybrids grown nowadays contain 'non-ripening mutations' that slow ripening and improve shelf life, but adversely affect flavor and color. We report substantial, targeted control of tomato softening, without affecting other aspects of ripening, by silencing a gene encoding a pectate lyase.

Indexed as

FruitGene SilencingGene TargetingGenetic EnhancementPlants, Genetically ModifiedPolysaccharide-LyasesSolanum lycopersicumpectate lyasePolysaccharide-Lyases

Identifiers

PMID27454737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.