Evidence map›Paper›PMID 27454168›Full record

ArticleBMC medical informatics and decision making2016

Secure Multi-pArty Computation Grid LOgistic REgression (SMAC-GLORE).

Haoyi Shi, Chao Jiang, Wenrui Dai, Xiaoqian Jiang, Yuzhe Tang, Lucila Ohno-Machado, Shuang Wang

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Being Bayesian in the 2020s: opportunities and challenges in the practice of modern applied Bayesian statistics.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Privacy-preserving logistic regression with secret sharing.BMC medical informatics and decision making · 2022
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haoyi ShiDepartment of Biomedical Informatics, University of California, San Diego, CA, 92093, USA.
Chao JiangDepartment of Biomedical Informatics, University of California, San Diego, CA, 92093, USA.
Wenrui DaiDepartment of Biomedical Informatics, University of California, San Diego, CA, 92093, USA.
Xiaoqian JiangDepartment of Biomedical Informatics, University of California, San Diego, CA, 92093, USA.
Yuzhe TangDepartment of Electrical Engineering and Computer Science, Syracuse University, Syracuse, NY, 13210, USA.
Lucila Ohno-MachadoDepartment of Biomedical Informatics, University of California, San Diego, CA, 92093, USA.
Shuang WangDepartment of Biomedical Informatics, University of California, San Diego, CA, 92093, USA. shw070@ucsd.edu.

Funding

iDASH: Integrating Data for Analysis, Anonymization, and SharingU54HL108460 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2010 to 2015
$19.1M
Privacy preserving technologies for human genome data analysis and disseminationR01HG007078 · NHGRI · TRUSTEES OF INDIANA UNIVERSITY · PI TANG, HAIXU, WANG, XIAOFENG · 2013 to 2015
$886k
Protection of Records: Privacy (PReP) Technology for Medical ResearchR00LM011392 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN · 2013 to 2015
$650k
Protecting the pRivacy Of Genomes in REsearch StudieS (PROGRESS)R00HG008175 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, SHUANG · 2016 to 2018
$527k
Protect Privacy of Healthcare Data in the CloudR21LM012060 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN · 2014 to 2015
$376k
Protecting the pRivacy Of Genomes in Research StudieS (PROGRESS)K99HG008175 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, SHUANG · 2014 to 2015
$100k
NHGRI NIH HHS K99 HG008175NHGRI NIH HHS R00 HG008175NHGRI NIH HHS R01 HG007078NHLBI NIH HHS U54 HL108460NLM NIH HHS R00 LM011392NLM NIH HHS R21 LM012060
6 · The paper itself

Abstract

backgroundIn biomedical research, data sharing and information exchange are very important for improving quality of care, accelerating discovery, and promoting the meaningful secondary use of clinical data. A big concern in biomedical data sharing is the protection of patient privacy because inappropriate information leakage can put patient privacy at risk.

methodsIn this study, we deployed a grid logistic regression framework based on Secure Multi-party Computation (SMAC-GLORE). Unlike our previous work in GLORE, SMAC-GLORE protects not only patient-level data, but also all the intermediary information exchanged during the model-learning phase.

resultsThe experimental results demonstrate the feasibility of secure distributed logistic regression across multiple institutions without sharing patient-level data.

conclusionsIn this study, we developed a circuit-based SMAC-GLORE framework. The proposed framework provides a practical solution for secure distributed logistic regression model learning.

Indexed as

Logistic ModelsRegression AnalysisBiomedical ResearchHumans

Identifiers

PMID27454168
PMCPMC4959358

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.