Evidence map›Paper›PMID 27454109›Full record

ArticleAIDS care2017

A pedigree-based proxy measure of genetic predisposition of drinking and alcohol use among female sex workers in China: a cross-sectional study.

Chen Zhang, Xiaoming Li, Yu Liu, Shan Qiao, Shaobing Su, Liying Zhang, Yuejiao Zhou

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Chen Zhanga Division of Epidemiology , Vanderbilt University , Nashville , TN , USA.
Xiaoming Lib Department of Health Promotion, Education, and Behavior, Arnold School of Public Health , University of South Carolina , Columbia , SC , USA.
Yu Liua Division of Epidemiology , Vanderbilt University , Nashville , TN , USA.
Shan Qiaob Department of Health Promotion, Education, and Behavior, Arnold School of Public Health , University of South Carolina , Columbia , SC , USA.
Shaobing Suc Department of Psychology , Tuft University , Medford , MA , USA.
Liying Zhangd Department of Pediatrics , Wayne State University , Detroit , MI , USA.
Yuejiao Zhoue Department of HIV/STD Prevention , Guangxi CDC , Nanning , Guangxi , China.
University of South Carolina · USVanderbilt University · USGuangxi Center for Disease Prevention and Control · CNTufts University · USWayne State University · US

Funding

Venue-based HIV and alcohol use risk reduction among female sex workers in ChinaR01AA018090 · NIAAA · WAYNE STATE UNIVERSITY · PI LI, XIAOMING · 2008 to 2012
$2.6M
NIAAA NIH HHS R01 AA018090
6 · The paper itself

Abstract

Scientific evidence has suggested that genetic factors accounted for more than half of the vulnerability of developing alcohol use problems. However, collecting genetic data poses a significant challenge for most population-based behavioral studies. The aim of this study was to assess the utilities of a pedigree-based proxy measure of genetic predisposition of drinking (GPD) and its effect on alcohol use behaviors as well as its interactions with personal and environmental factors. In the current study, cross-sectional data were collected from 700 female sex workers (FSW) in Guangxi, China. Participants provided information on a pedigree-based proxy measure of GPD and their alcohol use behaviors. Chi-square and independent t-test was applied for examining the bivariate associations between GPD and alcohol use behaviors; multivariate and ordinal regression models were used to examine the effect of GPD on alcohol use. This study found that women with a higher composite score of GPD tended to have a higher risk of alcohol use problem compared to their counterparts (p < .05). GPD was a significant predictor of alcohol use problems (p < .05), especially among women who had mental health issues or lack of health cares. The pedigree-based measure provided a useful proxy of GPD among participants. Both FSW's mental health and health care access interact with GPD and affect their drinking patterns. By understanding the genetic basis of alcohol use, we can develop scalable and efficacious interventions that will take into consideration the individual risk profile and environmental influences.

Indexed as

PedigreeSex WorkersAlcohol DrinkingAlcoholismChinaCross-Sectional StudiesFemaleGene-Environment InteractionGenetic Predisposition to DiseaseHumansChinafemale sex workersGenetic disposition of drinking

Identifiers

PMID27454109
PMCPMC6102057
OpenAlexW2480885988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.