Evidence map›Paper›PMID 27453921›Full record

ArticleCurrent opinion in behavioral sciences2015

Brain estrogen production and the encoding of recent experience.

Daniel M Vahaba, Luke Remage-Healey

Abstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. A brain for all seasons: An in vivo MRI perspective on songbirds.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2022
    Review
  4. Adverse Effects of Aromatase Inhibition on the Brain and Behavior in a Nonhuman Primate.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel M VahabaNeuroscience & Behavior Program, Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA, USA 01003.
Luke Remage-HealeyNeuroscience & Behavior Program, Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA, USA 01003.
University of Massachusetts Amherst · US

Funding

Rapid Estrogen Signaling in Brain Circuits that Guide Complex BehaviorR01NS082179 · NINDS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LUKE R REMAGE-HEALEY · 2014 to 2026
$3.8M
NINDS NIH HHS R01 NS082179
6 · The paper itself

Abstract

The vertebrate central nervous system integrates cognition and behavior, and it also acts as both a source and target for steroid hormones like estrogens. Recent exploration of brain estrogen production in the context of learning and memory has revealed several common themes. First, across vertebrates, the enzyme that synthesizes estrogens is expressed in brain regions that are characterized by elevated neural plasticity and is also integral to the acquisition, consolidation, and retrieval of recent experiences. Second, measurement and manipulation of estrogens reveal that the period following recent sensory experience is linked to estrogenic signaling in brain circuits underlying both spatial and vocal learning. Local brain estrogen production within cognitive circuits may therefore be important for the acquisition and/or consolidation of memories, and new directions testing these ideas will be discussed.

Identifiers

PMID27453921
PMCPMC4955874
OpenAlexW2177017277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.