ArticleCurrent environmental health reports2014
Cadmium and Reproductive Health in Women: A Systematic Review of the Epidemiologic Evidence.
Article in Current environmental health reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Dietary interventions to reduce heavy metal exposure in antepartum and postpartum women: a systematic review.Women's health nursing (Seoul, Korea) · 2024Pooled it
- The relationship between cadmium exposure and preeclampsia: a systematic review and meta-analysis.Frontiers in medicine · 2023Pooled it
- Cadmium exposure and risk of adverse pregnancy and birth outcomes: a systematic review and dose-response meta-analysis of cohort and cohort-based case-control studies.Journal of exposure science & environmental epidemiology · 2021Pooled it
- From Environmental to Possible Occupational Exposure to Risk Factors: What Role Do They Play in the Etiology of Endometriosis?International journal of environmental research and public health · 2021Pooled it
- Environmental contaminants and preeclampsia: a systematic literature review.Journal of toxicology and environmental health. Part B, Critical reviews · 2018Pooled it
- Trace Element Dyshomeostasis as a Mediator of Toxic Metal-Induced Reproductive Dysfunction: Mechanistic Insights and Future Perspectives.Biological trace element research · 2026Review
- Review
- Body mass index and sleep duration may regulate the effect of heavy metals on age at menopause.BMC public health · 2025Article
- Article
- Cadmium levels in maternal blood, placenta, and cord blood in relation to preeclampsia and fetal growth: a case-control study in China.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- A Prospective Ultrasound Study of Whole Blood Metals and Incidence of Uterine Leiomyomata.Environmental health perspectives · 2025Article
- Article
- Urinary cadmium and endometriosis prevalence in a US nationally representative sample: results from NHANES 1999-2006.Human reproduction (Oxford, England) · 2023Article
- Article
- Individual, Independent, and Joint Associations of Toxic Metals and Manganese on Hypertensive Disorders of Pregnancy: Results from the MIREC Canadian Pregnancy Cohort.Environmental health perspectives · 2023Article
- Review
- Environmental toxicants and placental function.Best practice & research. Clinical obstetrics & gynaecology · 2022Review
- Review
- Review
- Spatial variation and association between maternal chemical fertilizer exposure and preterm birth in a rural area in Northern China.Environmental science and pollution research international · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
An evolving body of evidence supports that cadmium, a non-essential heavy metal, may be associated with multiple adverse women's reproductive health outcomes. Our objective was to conduct a systematic review of epidemiologic studies that evaluated cadmium exposure and the following reproductive health outcomes: puberty/menarche, fertility, time to pregnancy, pregnancy loss, preeclampsia, endometriosis, uterine leiomyoma, and menopause. Twenty-two studies were identified based upon our search criteria. Available evidence was inadequate to draw meaningful conclusions for most of the reproductive outcomes studied. The strongest evidence was for a possible association between cadmium and preeclampsia, which was limited to cross-sectional studies. Some evidence, although conflicting, was also observed for fertility related outcomes. This lack of evidence underscores the need for additional research on cadmium and women's reproductive health outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.