Evidence map›Paper›PMID 27453802›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2016

Polygenic Risk for Externalizing Psychopathology and Executive Dysfunction in Trauma-Exposed Veterans.

Naomi Sadeh, Erika J Wolf, Mark W Logue, Joanna Lusk, Jasmeet P Hayes, Regina E McGlinchey, William P Milberg, Annjanette Stone, Steven A Schichman, Mark W Miller

Open access · greenAbstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Naomi SadehNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine.
Erika J WolfNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine.
Mark W LogueResearch Service, VA Boston Healthcare System, Boston, MA; Biomedical Genetics, Boston University School of Medicine, Boston, MA; Department of Biostatistics, Boston University School of Public Health.
Joanna LuskNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System.
Jasmeet P HayesNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine.
Regina E McGlincheyTranslational Research Center for TBI and Stress Disorders and Geriatric Research, Educational and Clinical Center, VA Boston Healthcare System; Department of Psychiatry, Harvard Medical School.
William P MilbergTranslational Research Center for TBI and Stress Disorders and Geriatric Research, Educational and Clinical Center, VA Boston Healthcare System; Department of Psychiatry, Harvard Medical School.
Annjanette StonePharmacogenomics Analysis Laboratory, Research Service, Central Arkansas Veterans Healthcare System.
Steven A SchichmanPharmacogenomics Analysis Laboratory, Research Service, Central Arkansas Veterans Healthcare System.
Mark W MillerNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System; Department of Psychiatry, Boston University School of Medicine.
Boston University · USCentral Arkansas Veterans Healthcare System · USUniversity School · USVA Boston Healthcare System · USHarvard University · USNational Center for PTSD · US

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI Sarah Hartz · 1989 to 2026
$162.7M
The Effects of Cannabis Legalization and Persistent Use: A Longitudinal Study of Two Twin CohortsR01DA042755 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Jarrod Martin Ellingson, SOO H RHEE · 2017 to 2026
$9.9M
The Genetics of Negative Conflict BehaviorR01MH079806 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MILLER, MARK W · 2007 to 2011
$1.5M
Neuroimaging Genetics of PTSDR21MH102834 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MILLER, MARK W · 2014 to 2015
$355k
Analysis of RORA and other candidate genes in PTSDI01BX002150 · VA · VA BOSTON HEALTH CARE SYSTEM · PI MILLER, MARK W · 2013 to 2015
–
The Structure of PTSD ComorbidityI01CX000431 · VA · VA BOSTON HEALTH CARE SYSTEM · PI MILLER, MARK W · 2011 to 2014
–
BLRD VA I01 BX002150CSRD VA I01 CX000431NIAAA NIH HHS U10 AA008401NIDA NIH HHS R01 DA042755NIMH NIH HHS R01 MH079806NIMH NIH HHS R21 MH102834
6 · The paper itself

Abstract

The frequent co-occurrence of antisocial behavior and other disinhibited phenotypes reflects a highly heritable externalizing spectrum. We examined the molecular genetic basis of this spectrum by testing polygenic associations with psychopathology symptoms, impulsive traits, and cognitive functions in two samples of primarily military veterans (

Indexed as

genesimpulsivityinhibitory controlinternalizingveteransworking memory

Identifiers

PMID27453802
PMCPMC4951156
OpenAlexW2191101121

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.