ArticleCosmetics2016
Impact of Cosmetic Lotions on Nanoparticle Penetration through
Article in Cosmetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- From exposure to oncogenesis: a review on the multifaceted roles of microplastics in tumor initiation and progression.Journal of translational medicine · 2025Review
- The Presence of Micro- and Nanoplastics in Food and the Estimation of the Amount Consumed Depending on Dietary Patterns.Molecules (Basel, Switzerland) · 2025Review
- Nanostructured Lipid Carriers for Sustained Release and Enhanced Delivery ofPharmaceutics · 2025Article
- Advantages and therapeutic applications of different semisolids as vehicles for nano-based systems.Therapeutic delivery · 2025Review
- Alopecia Management Potential of Rosemary-Based Nanoemulgel Loaded with Metformin: Approach Combining Active Essential Oil and Repurposed Drug.International journal of nanomedicine · 2025Article
- Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review.Cancers · 2024Review
- Review
- The Other Side of Plastics: Bioplastic-Based Nanoparticles for Drug Delivery Systems in the Brain.Pharmaceutics · 2023Review
- Immunomodulatory effects of nanoparticles on dendritic cells in a model of allergic contact dermatitis: importance of PD-L2 expression.Scientific reports · 2023Article
- Immunomodulatory Effects of Nanoparticles on Dendritic Cells in a Model of Allergic Contact Dermatitis - Importance of PD-L2 Expression.Research square · 2023Article
- Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals-What We Know So Far.Materials (Basel, Switzerland) · 2023Review
- Atmospheric micro (nano) plastics: future growing concerns for human health.Air quality, atmosphere, & health · 2023Review
- Review
- Derivatives of Plastics as Potential Carcinogenic Factors: The Current State of Knowledge.Cancers · 2022Review
- Micro/nano-plastics occurrence, identification, risk analysis and mitigation: challenges and perspectives.Re/views in environmental science and bio/technology · 2022Review
- Impact of Microplastics and Nanoplastics on Human Health.Nanomaterials (Basel, Switzerland) · 2021Review
- Experimental measurements and numerical simulations of the transport and retention of nanocrystal CdSe/ZnS quantum dots in saturated porous media: effects of pH, organic ligand, and natural organic matter.Environmental science and pollution research international · 2021Article
- Environmental fate, toxicity and risk management strategies of nanoplastics in the environment: Current status and future perspectives.Journal of hazardous materials · 2021Review
- The Role of Extracellular Vesicles in the Skin and Their Interactions with Nanoparticles.World journal of nanoscience and nanotechnology · 2020Article
- Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Understanding the interactions of nanoparticles (NPs) with skin is important from a consumer and occupational health and safety perspective, as well as for the design of effective NP-based transdermal therapeutics. Despite intense efforts to elucidate the conditions that permit NP penetration, there remains a lack of translatable results from animal models to human skin. The objectives of this study are to investigate the impact of common skin lotions on NP penetration and to quantify penetration differences of quantum dot (QD) NPs between freshly excised human and mouse skin. QDs were mixed in 7 different vehicles, including 5 commercial skin lotions. These were topically applied to skin using two exposure methods; a petri dish protocol and a Franz diffusion cell protocol. QD presence in the skin was quantified using Confocal Laser Scanning Microscopy. Results show that the commercial vehicles can significantly impact QD penetration in both mouse and human skin. Lotions that contain alpha hydroxyl acids (AHA) facilitated NP penetration. Lower QD signal was observed in skin studied using a Franz cell. Freshly excised human skin was also studied immediately after the sub-cutaneous fat removal process, then after 24 hours rest
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.