ArticleEnvironmental epigenetics2016
Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study.
Article in Environmental epigenetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Chemical and climatic environmental exposures and epigenetic aging: A systematic review.Environmental research · 2025Pooled it
- Pooled it
- The Impact of Air Pollution on Our Epigenome: How Far Is the Evidence? (A Systematic Review).Current environmental health reports · 2018Pooled it
- DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis.Blood · 2018Pooled it
- Transcending genome-wide association studies to create useful multi-omic views of glaucoma.Progress in retinal and eye research · 2026Review
- How Ambient Pollutants Accelerate Aging: Bridging Epigenetics, Age-Stratified Effects, and Public Health Interventions.Environment & health (Washington, D.C.) · 2026Article
- Acute biological age as a determinant of adverse outcomes requiring hospitalization in Danish emergency department patients.Communications medicine · 2026Article
- Long-term exposure to ambient air pollution and epigenetic age acceleration in children.American journal of epidemiology · 2025Article
- Immortality Reconsidered: Clinical Challenges at the Frontier of Plastic Surgery.Journal of clinical medicine · 2025Review
- Impact of Air Pollution on Chronic Airway Narrowing.Cureus · 2025Article
- The Joint Effects of Exposure to Ambient Long-term Air Pollution and Short-term Heat on Epigenetic Aging in the Health and Retirement Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Ageing Trajectories: Exposome-Driven Pathobiological Mechanisms and Implications for Prevention from Blue Zones and Italian Longevity Hotspots Such as Cilento and Sicilian Mountain Villages.International journal of molecular sciences · 2025Review
- Air Pollution and Effects of Tropospheric Ozone (OInternational journal of environmental research and public health · 2025Review
- Early-life exposure to secondhand smoke and polycyclic aromatic hydrocarbons: associations with epigenetic aging among children.Environmental epigenetics · 2025Article
- Review
- Multi-omic integration reveals alterations in nasal mucosal biology that mediate air pollutant effects on allergic rhinitis.Allergy · 2024Article
- Neighborhood-level deprivation and survival in lung cancer.BMC cancer · 2024Article
- Effect of air pollution on asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Review
- To promote healthy aging, focus on the environment.Nature aging · 2023Review
- Air pollution and epigenetic aging among Black and White women in the US.Environment international · 2023Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundAmbient particles have been shown to exacerbate measures of biological aging; yet, no studies have examined their relationships with DNA methylation age (DNAm-age), an epigenome-wide DNA methylation based predictor of chronological age.
objectiveWe examined the relationship of DNAm-age with fine particulate matter (PM
methodsWe used validated spatiotemporal models to generate 1-year PM
resultsAfter adjusting for covariates, a 1-µg/m
conclusionOur results support an association of long-termambient particle levels with DNAm-age and suggest that DNAm-age is a biomarker of particle-related physiological processes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.