ReviewJournal of medicine and life
The association between Diabetes mellitus and Depression.
Review in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 270 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
270 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Integrating Mental Health into Diabetes Care: Closing the Treatment Gap for Better Outcomes-A Systematic Review.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Burden of psychological symptoms and disorders among individuals with hepatitis B: a systematic review, meta-analysis and meta-regression.Frontiers in psychiatry · 2025Pooled it
- Effects of Integrated Care Approaches to Address Co-occurring Depression and Diabetes: A Systematic Review and Meta-analysis.Diabetes care · 2024Pooled it
- Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis.BMJ open diabetes research & care · 2024Pooled it
- The impact of food insecurity on mental health among older adults residing in low- and middle-income countries: A systematic review.PloS one · 2024Pooled it
- Salivary Biomarkers Associated with Psychological Alterations in Patients with Diabetes: A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Efficacy of eHealth Interventions for Adults with Diabetes: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- The Effect of Telenursing Using Self-care Education Podcasts on Anxiety and Quality of Life of Patients with Diabetic Retinopathy Undergoing Intravitreal Injection: A Randomized Clinical Trail.International journal of community based nursing and midwifery · 2026Trial
- The Influence of Depression, Positive Health Behaviors, and Weight Status on Glycated Hemoglobin: A Sequential Mediation Analysis of the INDEPENDENT Trial.Journal of general internal medicine · 2025Trial
- Strategies for Fidelity Monitoring a Solution-Focused Brief Intervention in a Randomized Clinical Trial.Journal of clinical psychology in medical settings · 2025Trial
- Factors influencing diabetes treatment satisfaction in the INtegrating DEPrEssioN and Diabetes treatmENT randomized clinical trial: A multilevel model analysis.Diabetic medicine : a journal of the British Diabetic Association · 2024Trial
- Effectiveness of a Digital Health Intervention Leveraging Reinforcement Learning: Results From the Diabetes and Mental Health Adaptive Notification Tracking and Evaluation (DIAMANTE) Randomized Clinical Trial.Journal of medical Internet research · 2024Trial
- Addressing depression and comorbid health conditions through solution-focused brief therapy in an integrated care setting: a randomized clinical trial.BMC primary care · 2024Trial
- Curcumin Reduces Depression in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.Nutrients · 2024Trial
- The Efficacy of Double-Heart Nursing in Combination with Seaweed Polysaccharide for Patients with Coronary Heart Disease Complicated with Diabetes: A Pilot, Randomized Clinical Trial.Disease markers · 2022Trial
- Brain-derived neurotrophic factor in diabetes: A promising target for cognitive restoration.iScience · 2026Review
- Empagliflozin mitigates depression-like behavior in diabetic mice via putative CRFNaunyn-Schmiedeberg's archives of pharmacology · 2026Article
- 25(OH)D modifies the relationship between depressive symptoms and chronic kidney disease in diabetic patients.International urology and nephrology · 2026Article
- Review
- Interrelationship Between Socioeconomic Status, Depression, and Neuropathy in People with Diabetes: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
210 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledDepression occurrence is two to three times higher in people with diabetes mellitus, the majority of the cases remaining under-diagnosed. The purpose of this review was to show the links between depression and diabetes, point out the importance of identifying depression in diabetic patients and identify the possible ways to address both diseases. Possible common pathophysiological mechanisms as stress and inflammation were explained, while emphasis was made on screening for depression in diabetic patients. An important aspect for the diabetic specialist would be the understanding of the common origins of diabetes and depression and the awareness of this quite common comorbidity, in order to improve the outcomes of both diseases. ABBREVIATIONS: DALYS = disability adjusted life years, DSM-5 = American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, DM1 = Type 1 diabetes mellitus, DM2 = Type 2 diabetes mellitus, HPA-axis = hypothalamus - pituitary - adrenal axis, SNS = sympathetic nervous system, BDI = Beck Depression Inventory, CES-D = Centre for Epidemiologic Studies Depression Scale, HADS = Hospital Anxiety and Depression Scale, PHQ = Patient Health Questionnaire.
Indexed as
Identifiers
27453739PMC4863499What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.