Evidence map›Paper›PMID 27453220›Full record

ArticleEpidemiology and infection2016

Isolation of Bartonella henselae, Bartonella koehlerae subsp. koehlerae, Bartonella koehlerae subsp. bothieri and a new subspecies of B. koehlerae from free-ranging lions (Panthera leo) from South Africa, cheetahs (Acinonyx jubatus) from Namibia and captive cheetahs from California.

S Molia, R W Kasten, M J Stuckey, H J Boulouis, J Allen, G M Borgo, J E Koehler, C C Chang, B B Chomel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Two novelFrontiers in microbiology · 2023
    Article
  3. Article
  4. Review
  5. Comparative Ecology ofFrontiers in veterinary science · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

S MoliaDepartment of Population Health and Reproduction,School of Veterinary Medicine,University of California,Davis,CA,USA.
R W KastenDepartment of Population Health and Reproduction,School of Veterinary Medicine,University of California,Davis,CA,USA.
M J StuckeyDepartment of Population Health and Reproduction,School of Veterinary Medicine,University of California,Davis,CA,USA.
H J BoulouisUniversité Paris-Est, Ecole Nationale Vétérinaire d'Alfort,UMR BIPAR,Maisons Alfort,Cedex France.
J AllenSan Diego Zoo Safari Park,Escondido,CA,USA.
G M BorgoMicrobial Pathogenesis and Host Defense Program, andDivision of Infectious Diseases,University of California,San Francisco,CA,USA.
J E KoehlerMicrobial Pathogenesis and Host Defense Program, andDivision of Infectious Diseases,University of California,San Francisco,CA,USA.
C C ChangGraduate Institute of Microbiology and Public Health,School of Veterinary Medicine,National Chung Hsing University,Taichung,Taiwan.
B B ChomelDepartment of Population Health and Reproduction,School of Veterinary Medicine,University of California,Davis,CA,USA.

Funding

Vaccines and Diagnostics TrialsU54AI065359 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARBOUR, ALAN G. · 2005 to 2013
$88.8M
Bartonella: dissecting niche-specific adaptation in a human pathogenR01AI103299 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KOEHLER, JANE E · 2013 to 2016
$1.9M
NIAID NIH HHS R01 AI103299NIAID NIH HHS U54 AI065359
6 · The paper itself

Abstract

Bartonellae are blood- and vector-borne Gram-negative bacteria, recognized as emerging pathogens. Whole-blood samples were collected from 58 free-ranging lions (Panthera leo) in South Africa and 17 cheetahs (Acinonyx jubatus) from Namibia. Blood samples were also collected from 11 cheetahs (more than once for some of them) at the San Diego Wildlife Safari Park. Bacteria were isolated from the blood of three (5%) lions, one (6%) Namibian cheetah and eight (73%) cheetahs from California. The lion Bartonella isolates were identified as B. henselae (two isolates) and B. koehlerae subsp. koehlerae. The Namibian cheetah strain was close but distinct from isolates from North American wild felids and clustered between B. henselae and B. koehlerae. It should be considered as a new subspecies of B. koehlerae. All the Californian semi-captive cheetah isolates were different from B. henselae or B. koehlerae subsp. koehlerae and from the Namibian cheetah isolate. They were also distinct from the strains isolated from Californian mountain lions (Felis concolor) and clustered with strains of B. koehlerae subsp. bothieri isolated from free-ranging bobcats (Lynx rufus) in California. Therefore, it is likely that these captive cheetahs became infected by an indigenous strain for which bobcats are the natural reservoir.

Indexed as

AcinonyxLionsAnimalsAnimals, ZooBartonellaBartonella henselaeBartonella InfectionsCaliforniaDNA, BacterialFemaleMaleNamibiaSequence Analysis, DNASouth AfricaDNA, BacterialAcynonyx jubatusBartonella henselaeBartonella koehleraecheetahlionPanthera leo

Identifiers

PMID27453220
PMCPMC9150282

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.