Evidence map›Paper›PMID 27453170›Full record

ArticleMaternal & child nutrition2017

Admission profile and discharge outcomes for infants aged less than 6 months admitted to inpatient therapeutic care in 10 countries. A secondary data analysis.

Carlos S Grijalva-Eternod, Marko Kerac, Marie McGrath, Caroline Wilkinson, June C Hirsch, Pascale Delchevalerie, Andrew J Seal

Registry-linked trialAbstract read
In one paragraph

Article in Maternal & child nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06372418 (Enhancing Growth and Development Among Malnourished Infants Recovering From a Serious Illness), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06372418 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Enhancing Growth and Development Among Malnourished Infants Recovering From a Serious Illness (IBAMI-2)

TypeinterventionalSponsorUniversity of OxfordRan2024 to 2027Enrolled250ConditionsMalnutrition, Infant, Breastfeeding, ExclusiveArmsBreastfeeding peer support intervention, Standard Care
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  19. Letter to the Editor of theJournal of nutritional science · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos S Grijalva-EternodUCL Institute for Global Health, 30 Guilford Street, London, WC1N 1EH, UK.ORCID 0000-0002-2461-9954
Marko KeracDepartment of Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Marie McGrathENN, 32 Leopold Street, Oxford, OX4 1TW, UK.
Caroline WilkinsonAction Contre la Faim (at the time of data submission), 14/16 Boulevard Douaumont, CS 80060 75854, Paris Cedex 17, France.
June C HirschAction Contre la Faim, 14/16 Boulevard Douaumont, CS 80060 75854, Paris Cedex 17, France.
Pascale DelchevalerieMedical Department, Médecins Sans Frontières, 46, Rue de l'Arbre Bénit, 1050, Bruxelles, France.
Andrew J SealUCL Institute for Global Health, 30 Guilford Street, London, WC1N 1EH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on the management of acute malnutrition in infants aged less than 6 months (infants <6mo) is scarce. To understand outcomes using current protocols, we analysed a sample of 24 045 children aged 0-60 months from 21 datasets of inpatient therapeutic care programmes in 10 countries. We compared the proportion of admissions, the anthropometric profile at admission and the discharge outcomes between infants <6mo and children aged 6-60 months (older children). Infants <6mo accounted for 12% of admissions. The quality of anthropometric data at admission was more problematic in infants <6mo than in older children with a greater proportion of missing data (a 6.9 percentage point difference for length values, 95% CI: 6.0; 7.9, P < 0.01), anthropometric measures that could not be converted to indices (a 15.6 percentage point difference for weight-for-length z-score values, 95% CI: 14.3; 16.9, P < 0.01) and anthropometric indices that were flagged as outliers (a 2.7 percentage point difference for any anthropometric index being flagged as an outlier, 95% CI: 1.7; 3.8, P < 0.01). A high proportion of both infants <6mo and older children were discharged as recovered. Infants <6mo showed a greater risk of death during treatment (risk ratio 1.30, 95% CI: 1.09; 1.56, P < 0.01). Infants <6mo represent an important proportion of admissions to therapeutic feeding programmes, and there are crucial challenges associated with their care. Systematic compilation and analysis of routine data for infants <6mo is necessary for monitoring programme performance and should be promoted as a tool to monitor the impact of new guidelines on care.

Indexed as

HospitalizationPatient DischargeAnthropometryChild, PreschoolFemaleHumansInfantInfant, NewbornMaleNutritional StatusNutrition AssessmentSevere Acute MalnutritionTreatment Outcomeanthropometryinfant and child nutritionmalnutritionmanagement of acute malnutritionmortalitywasting

Identifiers

PMID27453170
PMCPMC6865991

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.