ArticleChest2016
A Novel Spirometric Measure Identifies Mild COPD Unidentified by Standard Criteria.
Article in Chest, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: results from the Burden of Obstructive Lung Disease (BOLD) study.Respiratory research · 2023Pooled it
- Association of respiratory health with occupational exposures in the Burden of Obstructive Lung Disease (BOLD) cohort: a multinational longitudinal study.BMJ open respiratory research · 2026Observational
- Clinical Significance of Reduced Forced Expiratory Volume in 3 Seconds to Forced Expiratory Volume in 6 Seconds in Adults.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Small airways obstruction predicts cardiovascular disease incidence: a longitudinal study of UK Biobank.ERJ open research · 2026Article
- Small Airways Disease in Patients With COPD: A Question-and-Answer Approach for Everyday Clinical Practice.Chest · 2026Review
- Association between underdiagnosed and overdiagnosed chronic obstructive pulmonary disease with all-cause mortality.Journal of thoracic disease · 2025Article
- Innovation in technologies for monitoring lung function in patients with respiratory disease.Breathe (Sheffield, England) · 2025Article
- Small airway disease as a key factor in COPD: new perspectives and insights.Frontiers in medicine · 2025Review
- Article
- Establishment and application of reference equations for FEFJournal of thoracic disease · 2024Article
- Mortality risk associated with occupational exposures in people with small airways obstruction.PloS one · 2024Article
- Isolated small airways obstruction predicts future chronic airflow obstruction: a multinational longitudinal study.BMJ open respiratory research · 2023Article
- Optimal Threshold of FEVAmerican journal of respiratory and critical care medicine · 2023Article
- The Role of Pulmonary Function Testing in the Diagnosis and Management of COPD.Respiratory care · 2023Review
- The association of cardiorespiratory fitness with spirometric small airway obstruction.ERJ open research · 2023Article
- Occupational exposures and small airway obstruction in the UK Biobank Cohort.ERJ open research · 2023Article
- Prevalence of reduced lung diffusing capacity and CT scan findings in smokers without airflow limitation: a population-based study.BMJ open respiratory research · 2023Article
- Significance of FEVChest · 2022Observational
- Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review).Experimental and therapeutic medicine · 2021Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundIn chronic obstructive pulmonary disease, both smaller and larger airways are affected. FEV
methodsSeven thousand eight hundred fifty-three current and ex-smokers were evaluated for airflow obstruction by using recently defined linear iteratively derived equations of Hansen et al to determine lower limit of normal (LLN) equations for prebronchodilator FEV
resultsOf the 10,311 participants included in the COPDGene phase I study, participants with incomplete quantitative CT scanning or relevant spirometric data were excluded, resulting in 7,853 participants in the present study. Of 4,386 participants with FEV
conclusionsCurrent and ex-smokers with prebronchodilator FEV
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.