Evidence map›Paper›PMID 27452640›Full record

ArticleDiagnostic microbiology and infectious disease2016

Isolation and characterization of Helicobacter pylori recovered from gastric biopsies under anaerobic conditions.

Guillerm Ignacio Perez-Perez, Thinh Nguyen Van, Duong Thu Huong, Gao Zhan, Do Nguyet Anh, Nguyen Thi Nguyet, Loan Ta Thi, Nguyen Van Thinh, Nguyen Thi Hong-Hanh

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Postbiotics enhance the efficacy of derivative compound mouthwash against clinicalFrontiers in cellular and infection microbiology · 2025
    Article
  4. Article
  5. Journal of traditional and complementary medicine · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Guillerm Ignacio Perez-PerezDepartment of Medicine, NYU Langone Medical Center, New York, NY; Department Microbiology, NYU Langone Medical Center, New York, NY. Electronic address: Perezg02@med.nyu.edu.
Thinh Nguyen VanBuu Dien Hospital, Hanoi, Vietnam.
Duong Thu HuongInstitute of Biotechnology, Vietnam Academy of Sciences and Technology.
Gao ZhanDepartment of Medicine, NYU Langone Medical Center, New York, NY.
Do Nguyet AnhE Hospital, Hanoi, Vietnam.
Nguyen Thi NguyetInstitute of Biotechnology, Vietnam Academy of Sciences and Technology.
Loan Ta ThiInstitute of Biotechnology, Vietnam Academy of Sciences and Technology.
Nguyen Van ThinhInstitute of Biotechnology, Vietnam Academy of Sciences and Technology.
Nguyen Thi Hong-HanhInstitute of Biotechnology, Vietnam Academy of Sciences and Technology; Research and Development Center for Biotechnology CBT, VUSTA.
Vietnam Academy of Science and Technology · VNNYU Langone Health · USCzech Academy of Sciences, Institute of Biotechnology · CZViet Duc Hospital · VN

Funding

MATHEMATICAL MODELS OF H PYLORI GASTRIC COLONIZATIONR01GM063270 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BLASER, MARTIN J · 2000 to 2013
$3.1M
NIGMS NIH HHS R01 GM063270
6 · The paper itself

Abstract

BACKGROUND AND

aimHelicobacter pylori can survive long incubation periods under anaerobic conditions, and should be possible to isolate under anaerobic conditions. Our aim was to isolate H. pylori in anaerobic conditions, from gastric biopsies of H. pylori infected patients.

methodsWe enrolled 27 patients with bleeding (erosive) gastritis (mean age 36.3 years, 55.6% male) from Hanoi, Vietnam. H. pylori status was confirmed by qPCR.

resultsH. pylori were recovered under anaerobic and micro-aerobic conditions from gastric biopsies in 16 patients. Anaerobic conditions yielded significantly higher H. pylori recovery rates than micro-aerobic conditions (81.3% vs. 31.3%, P= 0.01). H. pylori isolates were characterized by PCR for specific virulence markers and the genotypes were similar to those previously described in this region of the world.

conclusionsH. pylori can be isolated under anaerobic conditions. These findings may provide new insight into the physiology of this human pathogen and help to identify the route of H. pylori transmission.

Indexed as

BiopsyAdultAnaerobiosisBacteriological TechniquesFemaleGastric MucosaGenotypeHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedPolymerase Chain ReactionSensitivity and SpecificityVietnamVirulence FactorsVirulence FactorsAnaerobic conditionsBacterial cultureH. pylori isolation

Identifiers

PMID27452640
PMCPMC5028281
OpenAlexW2465596375

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.