Evidence map›Paper›PMID 27452307›Full record

Trial reportJournal of veterinary pharmacology and therapeutics2017

The effects of clopidogrel and omeprazole on platelet function in normal dogs.

B E Thames, J Lovvorn, M G Papich, R Wills, T Archer, A Mackin, J Thomason

Open access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of veterinary pharmacology and therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Functionalization ofBioactive materials · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

B E ThamesDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
J LovvornDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
M G PapichDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
R WillsDepartments of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
T ArcherDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
A MackinDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
J ThomasonDepartment of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
Mississippi State University · USNorth Carolina State University · US

Funding

Summer Research Experience for Veterinary StudentsT35OD010432 · OD · MISSISSIPPI STATE UNIVERSITY · PI Barbara Lee-Faubert Kaplan, Temesgen Samuel · 2012 to 2026
$1.3M
NIH HHS T35 OD010432
6 · The paper itself

Abstract

Omeprazole is used concurrently with clopidogrel to reduce gastrointestinal adverse effects. In humans, the concurrent use of these two drugs can reduce the antiplatelet efficacy of clopidogrel. Our objective was to determine the effects of omeprazole and clopidogrel on platelet function in healthy dogs. A crossover study utilized turbidimetric aggregometry (ADP and collagen) and the PFA-100

Indexed as

AnimalsBlood PlateletsClopidogrelCross-Over StudiesDogsDrug Therapy, CombinationFemaleMaleOmeprazolePlatelet Aggregation InhibitorsPlatelet Function TestsProton Pump InhibitorsTiclopidineClopidogrelOmeprazolePlatelet Aggregation InhibitorsProton Pump InhibitorsTiclopidine

Identifiers

PMID27452307
PMCPMC6513019
OpenAlexW2481299576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.