Evidence map›Paper›PMID 27451108›Full record

ArticleJournal of psychiatric research2016

Clinical significance of mobile health assessed sleep duration and variability in bipolar disorder.

Christopher N Kaufmann, Anda Gershon, Lisa T Eyler, Colin A Depp

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Christopher N KaufmannDepartment of Psychiatry, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA; Stein Institute for Research on Aging, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. Electronic address: cnkaufmann@ucsd.edu.
Anda GershonChild and Adolescent Psychiatry, Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Palo Alto, CA, 94305, USA.
Lisa T EylerDepartment of Psychiatry, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA; Stein Institute for Research on Aging, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Colin A DeppDepartment of Psychiatry, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA; Stein Institute for Research on Aging, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Institute on Aging · USPalo Alto University · USUniversity of California, San Diego · US

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Dynamic Inflammatory and Mood Predictors of Cognitive Aging in Bipolar DisorderR01MH103318 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EYLER, LISA T · 2014 to 2018
$2.8M
Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental IllnessR01MH100417 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2013 to 2016
$2.1M
A Medication Adherence Intervention for Older Adults with Bipolar DisorderK23MH077225 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2007 to 2011
$763k
Sleep and Circadian Dysregulation in Pediatric Bipolar DisorderK01MH100433 · NIMH · STANFORD UNIVERSITY · PI GERSHON, ANDA · 2014 to 2017
$723k
Development of a Personalized Real-Time Intervention for Bipolar DisorderR34MH091260 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2010 to 2012
$691k
NIMH NIH HHS K01 MH100433NIMH NIH HHS K23 MH077225NIMH NIH HHS R01 MH100417NIMH NIH HHS R01 MH103318NIMH NIH HHS R34 MH091260NIMH NIH HHS T32 MH019934
6 · The paper itself

Abstract

objectiveSleep disturbances are prevalent, persistent, and impairing features of bipolar disorder. However, the near-term and cumulative impact of the severity and variability of sleep disturbances on symptoms and functioning remains unclear. We examined self-reported daily sleep duration and variability in relation to mood symptoms, medication adherence, cognitive functioning, and concurrent daily affect.

methodsForty-one outpatients diagnosed with bipolar disorder were asked to provide daily reports of sleep duration and affect collected via ecological momentary assessment with smartphones over eleven weeks. Measures of depressive and manic symptoms, medication adherence, and cognitive function were collected at baseline and concurrent assessment of affect were collected daily. Analyses examined whether sleep duration or variability were associated with baseline measures and changes in same-day or next-day affect.

resultsGreater sleep duration variability (but not average sleep duration) was associated with greater depressive and manic symptom severity, and lower medication adherence at baseline, and with lower and more variable ratings of positive affect and higher ratings of negative affect. Sleep durations shorter than 7-8 h were associated with lower same-day ratings of positive and higher same-day ratings of negative affect, however this did not extend to next-day affect.

conclusionsGreater cumulative day-to-day sleep duration variability, but not average sleep duration, was related to more severe mood symptoms, lower self-reported medication adherence and higher levels of negative affect. Bouts of short- or long-duration sleep had transient impact on affect. Day-to-day sleep variability may be important to incorporate into clinical assessment of sleep disturbances in bipolar disorder.

Indexed as

AdultBipolar DisorderFemaleHumansMaleMiddle AgedOutpatientsPsychiatric Status Rating ScalesSleep Wake DisordersSmartphoneTime FactorsAffective statesBipolar disorderSleep

Identifiers

PMID27451108
PMCPMC5064831
OpenAlexW2464564905

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.