SynthesisJACC. Cardiovascular imaging2017
Prognostic Value of Myocardial Scarring on CMR in Patients With Cardiac Sarcoidosis.
Synthesis in JACC. Cardiovascular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
98 citing papers in PubMed, 3 syntheses or guidelines pooled it, 232 citations in OpenAlex.
- Prognostic role of late gadolinium-enhanced MRI in confirmed and suspected cardiac sarcoidosis: meta-analysis.The international journal of cardiovascular imaging · 2024Pooled it
- Prognostic Value of RV Abnormalities on CMR in Patients With Known or Suspected Cardiac Sarcoidosis.JACC. Cardiovascular imaging · 2023Pooled it
- SCMR Position Paper (2020) on clinical indications for cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020Guideline
- Arrhythmias in Cardiac Sarcoidosis: Pathophysiology, Diagnostic Strategies, Risk Stratification for Sudden Cardiac Death, and Contemporary Management-A Narrative Review.Journal of clinical medicine · 2026Review
- Strict carbohydrate restriction enables volume-based FDG-PET/CT to outperform SUVmax for risk stratification in cardiac sarcoidosis.International journal of cardiology. Heart & vasculature · 2026Article
- Clinical and Imaging Abnormalities Associated With Inducible Ventricular Arrhythmias During Electrophysiologic Study in Patients With Cardiac Sarcoidosis and Mildly Impaired Left Ventricular Function.Journal of the American Heart Association · 2026Article
- Prognostic Value of Regadenoson Stress Perfusion CMR.Medical sciences (Basel, Switzerland) · 2026Article
- Article
- Severe Acute Decompensated Heart Failure in a Patient with Cardiac Sarcoidosis.Journal of clinical medicine · 2025Article
- Cardiac Magnetic Resonance in the Evaluation and Management of Nonischemic Cardiomyopathies.JACC. Heart failure · 2025Review
- Predicting Arrhythmic Risk in Cardiac Sarcoidosis Using Late Gadolinium Enhancement: Location, Location, Location.JACC. Cardiovascular imaging · 2025Article
- JCS/JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias.Journal of arrhythmia · 2025Article
- Cardiac Magnetic Resonance in Heart Failure: Diagnostic and Prognostic Assessments.Journal of cardiovascular development and disease · 2025Review
- Prognostic role of high-sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE-CS.ESC heart failure · 2025Observational
- Feasibility and Role of Cardiac Magnetic Resonance in Intensive and Acute Cardiovascular Care.Journal of clinical medicine · 2025Review
- Inflammation clashing onto myocardial susceptibility: a tale of two rare diseases-a case report.European heart journal. Case reports · 2025Article
- Cardiac Sarcoidosis: Clinical Insights, Diagnosis, and Management Strategies.Reviews in cardiovascular medicine · 2025Review
- Characterization of cardiac sarcoidosis in Iranian patients using cardiac magnetic resonance and positron emission tomography imaging techniques.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Article
- Role of Cardiac Magnetic Resonance in Inflammatory and Infiltrative Cardiomyopathies: A Narrative Review.Journal of clinical medicine · 2024Review
- The Role of Multimodality Imaging in Cardiomyopathy.Current cardiology reports · 2024Review
38 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThis study sought to perform a systematic review and meta-analysis to understand the prognostic value of myocardial scarring as evidenced by late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging in patients with known or suspected cardiac sarcoidosis.
backgroundAlthough CMR is increasingly used for the diagnosis of cardiac sarcoidosis, the prognostic value of CMR has been less well described in this population.
methodsPubMed, Cochrane CENTRAL, and metaRegister of Controlled Trials were searched for CMR studies with ≥1 year of prognostic data. Primary endpoints were all-cause mortality and a composite outcome of arrhythmogenic events (ventricular arrhythmia, implantable cardioverter-defibrillator shock, sudden cardiac death) plus all-cause mortality during follow-up. Summary effect estimates were generated with random-effects modeling.
resultsTen studies were included, involving a total of 760 patients with a mean follow-up of 3.0 ± 1.1 years. Patients had a mean age of 53 years, 41% were male, 95.3% had known extracardiac sarcoidosis, and 21.6% had known cardiac sarcoidosis. The average ejection fraction was 57.8 ± 9.1%. Patients with LGE had higher odds for all-cause mortality (odds ratio [OR]: 3.06; p < 0.03) and higher odds of the composite outcome (OR: 10.74; p < 0.00001) than those without LGE. Patients with LGE had an increased annualized event rate of the composite outcome (11.9% vs. 1.1%; p < 0.0001).
conclusionsIn patients with known or suspected cardiac sarcoidosis, the presence of LGE on CMR imaging is associated with increased odds of both all-cause mortality and arrhythmogenic events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.