ArticleEpilepsy & behavior : E&B2016
Prevalence of epileptiform discharges in healthy 11- and 12-year-old children.
Article in Epilepsy & behavior : E&B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Clinical Differentiation of Self-Limited Epilepsy With Autonomic Seizures (Panayiotopoulos Syndrome) and Childhood Migraine.Neurology. Clinical practice · 2026Article
- Clinical characteristics and diagnoses of 1213 children referred to a first seizure clinic.Epilepsia open · 2024Article
- Is epileptiform activity related to developmental language disorder? Findings from the HelSLI study.Clinical neurophysiology practice · 2023Article
- Electroencephalographic abnormalities in children with type 1 diabetes mellitus: a prospective study.Turkish journal of medical sciences · 2023Article
- The link between brain acidosis, breathing and seizures: a novel mechanism of action for the ketogenic diet in a model of infantile spasms.Brain communications · 2021Article
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Abstract
We sought to determine the prevalence of interictal epileptiform discharges (IEDs) in healthy 11- and 12-year-old children. Sixth grade students with no history of seizure, or neurologic or psychiatric disease, were enrolled in a longitudinal physical activity intervention study. Per study protocol, each student had two EEG recordings approximately 6months apart. Epileptiform discharges were present in 4 (2.9%) of 140 students: centrotemporal in three and generalized in one. In three children, the discharges were still present six months later. None of the children had developed seizures a minimum of one year after the second EEG. These results are consistent with those of two landmark European studies performed nearly a half century ago, before the modern era of digital EEG. Healthy 11- and 12-year-old children with no history of seizure may have centrotemporal or generalized epileptiform discharges on EEG, which can persist for at least 6months. Based on both our results and those of the two prior European studies, such discharges, if found incidentally in otherwise healthy children in this age group, should not prompt further evaluation or treatment.
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