Evidence map›Paper›PMID 27449925›Full record

Trial reportEuropean journal of nutrition2017

Reduced-fat Gouda-type cheese enriched with vitamin D

Yannis Manios, George Moschonis, Christina Mavrogianni, Eghm van den Heuvel, Cécile M Singh-Povel, Mairead Kiely, Kevin D Cashman

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Summary Outcomes of the ODIN Project on Food Fortification for Vitamin D Deficiency Prevention.International journal of environmental research and public health · 2018
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Yannis ManiosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El Venizelou Avenue, Kallithea, 17671, Athens, Greece. manios@hua.gr.
George MoschonisDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El Venizelou Avenue, Kallithea, 17671, Athens, Greece.
Christina MavrogianniDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El Venizelou Avenue, Kallithea, 17671, Athens, Greece.
Eghm van den HeuvelFrieslandCampina, Stationsplein 4, Post Box 1551, 3800 BN, Amersfoort, the Netherlands.
Cécile M Singh-PovelFrieslandCampina, Stationsplein 4, Post Box 1551, 3800 BN, Amersfoort, the Netherlands.
Mairead KielyCork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.
Kevin D CashmanCork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.
Harokopio University of Athens · GRFrieslandCampina (Netherlands) · NLUniversity College Cork · IE

Funding

European Commission 613977
6 · The paper itself

Abstract

objectiveThe primary aim of the present study was to examine the effectiveness of daily consumption of vitamin D

designThis is a single-blinded (i.e., to study participants), randomized, controlled food-based dietary intervention study.

methodsA sample of 79 postmenopausal women (55-75 years old) was randomized either to a control group (CG: n = 39) or an intervention group (IG: n = 40) that consumed, as part of their usual diet, 60 g of either non-enriched or vitamin D

resultsThere was a differential response of mean (95 % CI) serum 25(OH)D levels in the IG and CG, with the former increasing and the latter decreasing significantly over the eight weeks of the trial [i.e., by 5.1 (3.4, 6.9) nmol/L vs. -4.6 (-6.4, -2.8) nmol/L, P < 0.001, respectively]. The percentages of study participants with 25(OH)D levels <30 (deficiency) and <50 nmol/L (insufficiency) were significantly higher at follow-up in the CG compared to the IG (41.0 vs. 0 %, P < 0.001 and 74.4 vs. 47.5 %, P < 0.001, respectively). The emotional well-being scale of the HRQL score increased in the IG compared to a decrease in the CG (3.2 vs. -3.8, P = 0.028). However, none of the other seven scales of the HRQL score significantly differentiated between study groups (P > 0.1).

conclusionsConsumption of 60 g of vitamin D

Indexed as

CheeseFood, FortifiedAgedCholecalciferolDietFemaleFollow-Up StudiesGreeceHumansMiddle AgedPostmenopauseQuality of LifeReproducibility of ResultsSeasonsSingle-Blind MethodSurveys and QuestionnairesCholecalciferol25-Hydroxyvitamin DCheeseEnriched dairyPostmenopausal womenVitamin D

Identifiers

PMID27449925
OpenAlexW2482221805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.