Evidence map›Paper›PMID 27449698›Full record

ArticleBritish journal of pharmacology2016

The novel late Na

Sridharan Rajamani, Gongxin Liu, Nesrine El-Bizri, Donglin Guo, Cindy Li, Xiao-Liang Chen, Kristopher M Kahlig, Nevena Mollova, Elfatih Elzein, Jeff Zablocki and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Late IMedicinal research reviews · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Mitochondrial CaJournal of molecular and cellular cardiology · 2021
    Review
  9. Article
  10. Inhibition of voltage-gated NaHeart rhythm O2 · 2020
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. The novel late NaBritish journal of pharmacology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Sridharan RajamaniDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Gongxin LiuDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Nesrine El-BizriDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Donglin GuoDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Cindy LiDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Xiao-Liang ChenDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Kristopher M KahligDepartment of Biology, Gilead Sciences, Inc., Foster City, CA, USA.
Nevena MollovaDepartment of Drug Metabolism, Gilead Sciences, Inc., Foster City, CA, USA.
Elfatih ElzeinDepartment of Chemistry, Gilead Sciences, Inc., Foster City, CA, USA.
Jeff ZablockiDepartment of Chemistry, Gilead Sciences, Inc., Foster City, CA, USA.
Luiz BelardinelliDepartment of Clinical Research, Gilead Sciences, Inc., Foster City, CA, USA. luiz.belardinelli@gmail.com.
Gilead Sciences (United States) · USGilead Sciences (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeEnhanced late Na EXPERIMENTAL APPROACH: The effects of GS-6615 to inhibit late I KEY

resultsGS-6615 inhibited ATX-II enhanced late I CONCLUSIONS AND IMPLICATIONS: GS-6615 was a selective inhibitor of late I

Indexed as

AnimalsAnti-Arrhythmia AgentsHeartLong QT SyndromeMolecular StructureOxazepinesRabbitsSodium Channel BlockersSodium ChannelsAnti-Arrhythmia AgentseleclazineOxazepinesSodium Channel BlockersSodium Channels

Identifiers

PMID27449698
PMCPMC5056228
OpenAlexW2506776785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.