Evidence map›Paper›PMID 27449570›Full record

ArticleAnnals of epidemiology2016

Adverse childhood experiences and later life adult obesity and smoking in the United States.

David H Rehkopf, Irene Headen, Alan Hubbard, Julianna Deardorff, Yamini Kesavan, Alison K Cohen, Divya Patil, Lorrene D Ritchie, Barbara Abrams

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 60 citations in OpenAlex.

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  6. Body mass trajectories from adolescence to adulthood in the United States: Effects of racial identification and adverse childhood experiences.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025
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  12. Adverse childhood experiences and sleep links in a predominantly Black sample of overweight adults.Stress and health : journal of the International Society for the Investigation of Stress · 2023
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  16. Relationships among adverse childhood experiences, delay discounting, impulsivity, and diabetes self-management.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

David H RehkopfDepartment of Medicine, Stanford University School of Medicine, Stanford, CA. Electronic address: drehkopf@stanford.edu.
Irene HeadenDivision of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley.
Alan HubbardDivision of Biostatistics, School of Public Health, University of California, Berkeley, Berkeley.
Julianna DeardorffDivision of Maternal and Child Health, School of Public Health, University of California, Berkeley, Berkeley.
Yamini KesavanDivision of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley.
Alison K CohenDivision of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley.
Divya PatilDivision of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley.
Lorrene D RitchieDivision of Agriculture and Natural Resources, Nutrition Policy Institute, University of California, Oakland.
Barbara AbramsDivision of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley.
University of California, Berkeley · USStanford Medicine · USUniversity of California Division of Agriculture and Natural Resources · US

Funding

Intergenerational Obesity: Do Early Adversity and Pregnancy Explain Disparities?R01MD006104 · NIMHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ABRAMS, BARBARA FAYE · 2010 to 2014
$1.5M
Life course contexts and work - quantifying impacts on aging and chronic diseaseK01AG047280 · NIA · STANFORD UNIVERSITY · PI REHKOPF, DAVID H · 2014 to 2018
$632k
NIA NIH HHS K01 AG047280NIMHD NIH HHS R01 MD006104
6 · The paper itself

Abstract

purposePrior work demonstrates associations between physical abuse, household alcohol abuse, and household mental illness early in life with obesity and smoking. Studies, however, have not generally been in nationally representative samples and have not conducted analyses to account for bias in the exposure.

methodsWe used data from the 1979 U.S. National Longitudinal Survey of Youth to test associations between measures of adverse childhood experiences with obesity and smoking and used an instrumental variables approach to address potential measurement error of the exposure.

resultsModels demonstrated associations between childhood physical abuse and obesity at age 40 years (odds ratio [OR] 1.23; 95% confidence interval [CI], 1.00-1.52) and ever smoking (OR 1.83; 95% CI, 1.56-2.16), as well as associations between household alcohol abuse (OR 1.53; 95% CI, 1.31-1.79) and household mental illness (OR 1.29; 95% CI, 1.04-1.60) with ever smoking. We find no evidence of association modification by gender, socioeconomic position, or race and/or ethnicity. Instrumental variables analysis using a sibling's report of adverse childhood experiences demonstrated a relationship between household alcohol abuse and smoking, with a population attributable fraction of 17% (95% CI, 2.0%-37%) for ever smoking and 6.7% (95% CI, 1.6%-12%) for currently smoking.

conclusionsFindings suggest long-term impacts of childhood exposure to physical abuse, household alcohol abuse, and parental mental illness on obesity and smoking and that the association between household alcohol abuse and smoking is not solely due to measurement error.

Indexed as

Life Change EventsAdolescentAdultAge of OnsetAlcoholismChildChild AbuseCross-Sectional StudiesFamily CharacteristicsFemaleHumansLongitudinal StudiesMaleObesityParent-Child RelationsPrevalenceLife courseMeasurementObesitySmoking

Identifiers

PMID27449570
PMCPMC4966898
OpenAlexW2409723444

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.