ArticleArchives of physical medicine and rehabilitation2017
Negative Neurodynamic Tests Do Not Exclude Neural Dysfunction in Patients With Entrapment Neuropathies.
Article in Archives of physical medicine and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Nerve pathology and neuropathic pain after whiplash injury: a systematic review and meta-analysis.Pain · 2022Pooled it
- Mechanosensitivity during straight leg raise and slump neurodynamic tests in people with type 1 diabetes mellitus and diabetic peripheral neuropathy.The Journal of manual & manipulative therapy · 2026Article
- Neurological examination for cervical radiculopathy: a scoping review.BMC musculoskeletal disorders · 2025Article
- Understanding the Mechanosensitivity of the Median Nerve in Pre-Surgical Carpal Tunnel Syndrome Patients: A Correlational Study.Brain sciences · 2024Article
- Central Sensitization in Patients with Chronic Pain Secondary to Carpal Tunnel Syndrome and Determinants.Journal of pain research · 2023Article
- Does the efficacy of neurodynamic treatments depend on the presence and type of criteria used to define neural mechanosensitivity in spinally-referred leg pain? A systematic review and meta-analysis.The South African journal of physiotherapy · 2022Review
- Quantifying the Elasticity Properties of the Median Nerve during the Upper Limb Neurodynamic Test 1.Applied bionics and biomechanics · 2022Article
- [Entrapment neuropathies: a contemporary approach to pathophysiology, clinical assessment, and management : German version].Schmerz (Berlin, Germany) · 2021Review
- Application of digital infrared thermography for carpal tunnel syndrome evaluation.Scientific reports · 2021Article
- First rib dysfunction in patients with neck and shoulder pain: a Delphi investigation.The Journal of manual & manipulative therapy · 2021Article
- Clinical indicators to identify neuropathic pain in low back-related leg pain: protocol for a modified Delphi study.BMJ open · 2020Article
- Concurrent validity of a low-cost and time-efficient clinical sensory test battery to evaluate somatosensory dysfunction.European journal of pain (London, England) · 2019Article
- Entrapment neuropathies: a contemporary approach to pathophysiology, clinical assessment, and management.Pain reportsArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
objectiveTo examine differences in somatosensory phenotypes of patients with positive and negative neurodynamic tests and compare these with healthy participants.
designCase-control study.
settingUniversity department.
participantsPatients with electrodiagnostically confirmed carpal tunnel syndrome (CTS) (n=53) and people without CTS (n=26) participated in this study (N=79). Patients with CTS were subgrouped according to the results of the upper limb neurodynamic tests biasing the median nerve into patients with positive or negative neurodynamic tests.
interventionsNot applicable.
main outcome measureAll participants underwent quantitative sensory testing in the median innervated territory of their hand.
resultsOnly 46% of patients with CTS had positive neurodynamic tests. No differences were identified between groups for pain thresholds (P>.247). However, patients with CTS had increased mechanical (P<.0001) and thermal detection thresholds (P<.0001) compared with people without CTS. Patients with negative neurodynamic tests had a more pronounced vibration detection deficit (mean, 7.43±0.59) than people without CTS (mean, 7.89±0.22; P=.001). Interestingly, warm detection was the only domain differentiating positive (mean, 4.03°C±2.18°C) and negative neurodynamic test groups (6.09°C±3.70°C, P=.032), with patients with negative neurodynamic tests demonstrating increased loss of function.
conclusionsPatients with negative neurodynamic tests seem to have a more severe dysfunction of the unmyelinated fiber population. Our findings suggest that neurodynamic tests should not be used in isolation to judge neural involvement. Rather, they should be interpreted in the context of loss of function tests of the small fiber domain.
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