ArticleArchives of microbiology2016
Probiotic properties of Oxalobacter formigenes: an in vitro examination.
Article in Archives of microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- InducingKidney international reports · 2025Article
- Probiotics in the prevention and treatment of calcium oxalate kidney stones: mechanisms and therapeutic potential.Frontiers in microbiology · 2025Review
- Non-lactic acid bacteria probiotics isolated from intestine or various circumstances.Food science and biotechnology · 2024Review
- Altered Gut Microbiota as a Potential Risk Factor for Coronary Artery Disease in Diabetes: A Two-Sample Bi-Directional Mendelian Randomization Study.International journal of medical sciences · 2024Article
- Update on the Effect of the Urinary Microbiome on Urolithiasis.Diagnostics (Basel, Switzerland) · 2023Review
- Synbiotic supplementation and oxalate homeostasis in rats: focus on microbiota oxalate-degrading activity.Urolithiasis · 2022Article
- Review
- Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist.Applied and environmental microbiology · 2021Review
- The Relationship between Urinary Stones and Gut Microbiomeby 16S Sequencing.BioMed research international · 2020Article
- Zearalenone Changes the Diversity and Composition of Caecum Microbiota in Weaned Rabbit.BioMed research international · 2018Article
- Vertically and horizontally transmitted microbial symbionts shape the gut microbiota ontogenesis of a skin-mucus feeding discus fish progeny.Scientific reports · 2017Article
- Response of germ-free mice to colonization with O. formigenes and altered Schaedler flora.Applied and environmental microbiology · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Oxalobacter formigenes (O. formigenes) is a nonpathogenic, Gram-negative, obligate anaerobic bacterium that commonly inhabits the human gut and degrades oxalate as its major energy and carbon source. Results from a case-controlled study suggested that lack of O. formigenes colonization is a risk factor for recurrent calcium oxalate stone formation. Hence, O. formigenes colonization may prove to be an efficacious method for limiting calcium oxalate stone risk. However, challenges exist in the preparation of O. formigenes as a successful probiotic due to it being an anaerobe with fastidious growth requirements. Here we examine in vitro properties expected of a successful probiotic strain. The data show that the Group 1 O. formigenes strain OxCC13 is sensitive to pH < 5.0, persists in the absence of oxalate, is aerotolerant, and survives for long periods when freeze-dried or mixed with yogurt. These findings highlight the resilience of this O. formigenes strain to some processes and conditions associated with the manufacture, storage and distribution of probiotic strains.
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Registered trials
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