Evidence map›Paper›PMID 27448618›Full record

ReviewCurrent gastroenterology reports2016

Progress in Our Understanding of the Gut Microbiome: Implications for the Clinician.

Sara Iqbal, Eamonn M M Quigley

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sara IqbalDepartment of Medicine, Houston Methodist Hospital and Weill Cornell Medical College, 6550 Fannin St, SM 1001, Houston, TX, 77030, USA.
Eamonn M M QuigleyDepartment of Medicine, Houston Methodist Hospital and Weill Cornell Medical College, 6550 Fannin St, SM 1001, Houston, TX, 77030, USA. equigley@tmhs.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The investigation of the role of the microbial communities of our gastrointestinal tract (microbiota) has accelerated dramatically in recent years thanks to rapid developments in the technologies that allow us to fully enumerate and evaluate the full complement of bacterial species and strains that normally inhabit the gut. Laboratory studies in a range of inventive animal models continue to provide insights into the role of the microbiota in health and to generate plausible hypotheses relating to its potential involvement in the pathogenesis of human disease. Studies of the composition of human gut microbiota continue to accumulate but their interpretation needs to be tempered by an appreciation of the limitations of single-point-in-time studies of fecal samples from small study populations. Nevertheless, clinically important examples of a central role for microbiota-host interactions in disease pathogenesis have emerged and many more have been postulated but await confirmation in appropriately powered and conducted studies.

Indexed as

Gastrointestinal MicrobiomeAnti-Bacterial AgentsColorectal NeoplasmsDiarrheaGastrointestinal DiseasesGastrointestinal TractHumansInflammatory Bowel DiseasesIrritable Bowel SyndromeLiver DiseasesMetabolic SyndromeTerminology as TopicAnti-Bacterial AgentsAntibiotic-associated diarrheaBacteriaClostridium difficileColorectal cancerInflammatory bowel diseaseIrritable bowel syndromeLiver diseaseMicrobiomeMicrobiota

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.