ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2016
Upper Airway Collapsibility Assessed by Negative Expiratory Pressure while Awake is Associated with Upper Airway Anatomy.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: A systematic review and meta-analysis.Sleep medicine reviews · 2023Pooled it
- Models of anatomically based oropharyngeal rehabilitation with a multilevel approach for patients with obstructive sleep apnea: a meta-synthesis and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2020Pooled it
- Oropharyngeal enlargement in obstructive lung disease: quantification and machine learning.ERJ open research · 2025Article
- Neuro-Ophthalmological Disorders Associated with Obstructive Sleep Apnoea.International journal of molecular sciences · 2025Review
- Assessment of the correlation between the volume of tongue, oral cavity, tongue/oral cavity volume ratio and the upper airway in unilateral cleft subjects: A CBCT study.Oral radiology · 2025Article
- DISE with CPAP: a useful procedure to evaluate upper airway collapsibility.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Observational
- Relationship between airflow limitation in response to upper airway negative pressure during wakefulness and obstructive sleep apnea severity.Sleep & breathing = Schlaf & Atmung · 2024Article
- Phenotyping OSAH patients during wakefulness.Sleep & breathing = Schlaf & Atmung · 2022Article
- Critical closing pressure of the pharyngeal airway during routine drug-induced sleep endoscopy: feasibility and protocol.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Critical to Know Pcrit: A Review on Pharyngeal Critical Closing Pressure in Obstructive Sleep Apnea.Frontiers in neurology · 2022Review
- Effect of tube length on the buckling pressure of collapsible tubes.Computers in biology and medicine · 2021Article
- It's possible: why don't we do it?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- A Novel Model to Estimate Key Obstructive Sleep Apnea Endotypes from Standard Polysomnography and Clinical Data and Their Contribution to Obstructive Sleep Apnea Severity.Annals of the American Thoracic Society · 2021Article
- Measurement of upper airway resistances: A simple way to assess its collapsibility?Sleep & breathing = Schlaf & Atmung · 2020Observational
- Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle.Journal of clinical medicine · 2019Review
- More Than the Sum of the Respiratory Events: Personalized Medicine Approaches for Obstructive Sleep Apnea.American journal of respiratory and critical care medicine · 2019Review
- Obstructive sleep apnea: current perspectives.Nature and science of sleep · 2018Review
- Obstructive sleep apnea: focus on myofunctional therapy.Nature and science of sleep · 2018Review
- Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment.European respiratory review : an official journal of the European Respiratory Society · 2017Review
- Influence of interface and position on upper airway collapsibility assessed by negative expiratory pressure.Sleep & breathing = Schlaf & Atmung · 2017Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThere is a growing interest to develop a simple method to characterize the mechanisms leading to upper airway collapse in order to guide treatment options in patients with obstructive sleep apnea (OSA). Critical closing pressure (Pcrit) during sleep is able to predict the anatomical component of OSA. However, Pcrit is a laborious method that is only used for research purposes. The application of negative expiratory pressure (NEP) is a simple method to assess upper airway collapsibility that can be easily performed during wakefulness. We hypothesized that NEP will be, similarly to Pcrit, associated with upper airway anatomy assessed by computed tomography (CT) scan.
methodsPatients under investigation for OSA underwent polysomnography, CT of the upper airway, NEP while awake, and Pcrit during sleep. NEP was performed with -5 cm H
resultsTwenty-eight male subjects were studied (age 45 ± 13 y, body mass index 29.4 ± 4.9 kg/m
conclusionsNEP is a simple and promising method that is associated with the anatomical component of upper airway collapsibility. NEP may be valuable to select patients for noncontinuous positive airway pressure alternative therapies for OSA.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.