Evidence map›Paper›PMID 27447899›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2017

Incidence and survival time trends for Spanish children and adolescents with leukaemia from 1983 to 2007.

R Marcos-Gragera, J Galceran, C Martos, A L de Munain, M Vicente-Raneda, C Navarro, J R Quirós-Garcia, M-J Sánchez, E Ardanaz, M Ramos and 4 more

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Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence.International journal of environmental research and public health · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. ECLIM-SEHOP, a new platform to set up and develop international academic clinical trials for childhood cancer and blood disorders in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

R Marcos-GrageraEpidemiology Unit and Girona Cancer Registry (UERCG), Oncology Coordination Plan (PDO), Department of Health, Autonomous Government of Catalonia, Girona, Spain. rmarcos@iconcologia.net.ORCID http://orcid.org/0000-0001-9824-3657
J GalceranTarragona Cancer Registry, Foundation Society for Cancer Research and Prevention (FUNCA), Reus, Spain.
C MartosZaragoza Cancer Registry, Aragon Government, Saragossa, Spain.
A L de MunainBasque Country Cancer Registry, Basque Government, Vitoria-Gasteiz, Spain.
M Vicente-RanedaCommunity Valenciana Childhood Cancer Registry, Public Health Directorate, Conselleria de Sanitat Universal i Salut Pública, Generalitat Valenciana, Valencia, Spain.
C NavarroDepartment of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain.
J R Quirós-GarciaPublic Health Directorate, Asturias, Spain.
M-J SánchezGranada Cancer Registry, Andalusian School of Public Health, Granada, Spain.
E ArdanazNavarre Cancer Registry, Navarre Public Health Institute, Pamplona, Spain.
M RamosMallorca Cancer Registry, Epidemiology Department, Directorate-General of Public Health and Participation, Palma de Mallorca, Spain.
A MateosAlbacete Cancer Registry, Health and Social Welfare Authority, Albacete, Spain.
D SalmerónDepartment of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain.
S FelipeSpanish Childhood Cancer Registry (RETI-SEHOP), Spanish Society of Paediatric Haematology and Oncology, University of Valencia, Valencia, Spain.
R Peris-BonetSpanish Childhood Cancer Registry (RETI-SEHOP), Spanish Society of Paediatric Haematology and Oncology, University of Valencia, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe have analysed incidence and survival trends of children and adolescents with leukaemia registered in Spanish population-based cancer registries during the period 1983-2007.

methodsChildhood and adolescent leukaemia cases were drawn from the 11 Spanish population-based cancer registries. For survival, registries with data for the period 1991-2005 and follow-up until 31-12-2010 were included. Overall incidence trends were evaluated using joinpoint analysis. Observed survival rates were estimated using Kaplan-Meier, and trends were tested using the log-rank test.

resultsBased on 2606 cases (2274 children and 332 adolescents), the overall age-adjusted incidence rate (ASRw) of leukaemia was 47.9 cases per million child-years in children and 23.8 in adolescents. The ASRw of leukaemia increased with an annual percentage change of 9.6 % (95 % CI: 2.2-17.6) until 1990 followed by a stabilisation of rates. In adolescents, incidence did not increase. Five-year survival increased from 66 % in 1991-1995 to 76 % in 2001-2005. By age, survival was dramatically lower in infants (0) and adolescents (15-19) than in the other age groups and no improvement was observed. In both children and adolescents, differences in 5-year survival rates among major subgroups of leukaemias were significant.

conclusionsThe increasing incidence trends observed in childhood leukaemias during the study period were confined to the beginning of the period. Remarkable improvements in survival have been observed in Spanish children with leukaemias. However, this improvement was not observed in infants and adolescents.

Indexed as

AdolescentAdultAge FactorsChildChild, PreschoolFemaleFollow-Up StudiesHumansIncidenceInfantInfant, NewbornLeukemiaMaleNeoplasm StagingPrognosisRegistriesAdolescent leukaemiaCancer registryCancer survivalChildhood cancerChildhood leukaemiaGlobal health

Identifiers

PMID27447899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.