Evidence map›Paper›PMID 27447709›Full record

ReviewMedical & biological engineering & computing2017

Microfluidic microscopy-assisted label-free approach for cancer screening: automated microfluidic cytology for cancer screening.

Veerendra Kalyan Jagannadh, G Gopakumar, Gorthi R K Sai Subrahmanyam, Sai Siva Gorthi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical & biological engineering & computing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Machine Learning with Optical Phase Signatures for Phenotypic Profiling of Cell Lines.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Veerendra Kalyan JagannadhOptics and Microfluidics Instrumentation Lab, Department of Instrumentation and Applied Physics, Indian Institute of Science, Malleshwaram, Bangalore, 560012, India.
G GopakumarDepartment of Earth and Space Sciences, Indian Institute of Space Science and Technology, Thiruvananthapuram, Kerala, 695547, India.
Gorthi R K Sai SubrahmanyamDepartment of Earth and Space Sciences, Indian Institute of Space Science and Technology, Thiruvananthapuram, Kerala, 695547, India.
Sai Siva GorthiOptics and Microfluidics Instrumentation Lab, Department of Instrumentation and Applied Physics, Indian Institute of Science, Malleshwaram, Bangalore, 560012, India. saisiva.gorthi@iap.iisc.ernet.in.
Indian Institute of Science Bangalore · INIndian Institute of Space Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Each year, about 7-8 million deaths occur due to cancer around the world. More than half of the cancer-related deaths occur in the less-developed parts of the world. Cancer mortality rate can be reduced with early detection and subsequent treatment of the disease. In this paper, we introduce a microfluidic microscopy-based cost-effective and label-free approach for identification of cancerous cells. We outline a diagnostic framework for the same and detail an instrumentation layout. We have employed classical computer vision techniques such as 2D principal component analysis-based cell type representation followed by support vector machine-based classification. Analogous to criminal face recognition systems implemented with help of surveillance cameras, a signature-based approach for cancerous cell identification using microfluidic microscopy surveillance is demonstrated. Such a platform would facilitate affordable mass screening camps in the developing countries and therefore help decrease cancer mortality rate.

Indexed as

Early Detection of CancerHumansMass ScreeningMicrofluidicsMicroscopyNeoplasmsCancer diagnosticsCell identificationHigh-throughput imagingOptofluidic imaging

Identifiers

PMID27447709
OpenAlexW2503201113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.