Evidence map›Paper›PMID 27447478›Full record

ArticleJournal of gastrointestinal cancer2017

Free/Total Serum Prostate-Specific Antigen Ratio in Women with Colorectal Cancer Has Prognostic Significance.

Nüvit Duraker, Zeynep Civelek Çaynak, Didem Can Trabulus

Abstract read
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In one paragraph

Article in Journal of gastrointestinal cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nüvit DurakerDepartment of Surgery, SB Okmeydanı Training and Research Hospital, İstanbul, Turkey. nuvitduraker@gmail.com.
Zeynep Civelek ÇaynakDepartment of Surgery, Bayındır Levent Hospital, İstanbul, Turkey.
Didem Can TrabulusDepartment of Surgery, SB İstanbul Training and Research Hospital, İstanbul, Turkey.
Bayındır Hastanesi · TROkmeydanı Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe presence of prostate-specific antigen (PSA) in colon cancer tissues has been shown, but its clinical significance has not been known yet in colorectal cancer patients. We investigated the prognostic significance of percent free PSA value (free PSA/total PSA × 100) in female patients with colorectal cancer.

methodsThe serum concentrations of total and free PSA were measured by solid-phase two-site immunoradiometric assay in 184 patients.

resultsThe cancer-specific survival (CSS) of patients with percent free PSA value ≥35 was significantly better compared to that of patients with percent free PSA value <35 (CSS rate was 82.9 and 55.5 %, respectively; log-rank x

conclusionPercent free PSA value, calculated by serum total and free PSA levels, has prognostic significance in women with colorectal cancer. The studies with larger patient series, utilizing ultrasensitive PSA assays whose lowest detection limit is lower, are required for a clearer understanding of this issue.

Indexed as

AdultAgedAged, 80 and overColorectal NeoplasmsFemaleHumansKallikreinsMiddle AgedPrognosisProstate-Specific AntigenSurvival AnalysisSurvival RateYoung AdultKallikreinsKLK3 protein, humanProstate-Specific AntigenColorectal carcinomaFemale patientPercentage of free PSAPSASurvival

Identifiers

PMID27447478
OpenAlexW2487086936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.