ArticleFrontiers in veterinary science2016
Canine Detection of the Volatilome: A Review of Implications for Pathogen and Disease Detection.
Article in Frontiers in veterinary science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04578509 (Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva), which is not on this map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva (COVID-19)
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Remote Medical Scent Detection of Cancer and Infectious Diseases With Dogs and Rats: A Systematic Review.Integrative cancer therapiesPooled it
- Sniffer dogs performance is stable over time in detecting COVID-19 positive samples and agrees with the rapid antigen test in the field.Scientific reports · 2023Trial
- Scent dogs in detection of COVID-19: triple-blinded randomised trial and operational real-life screening in airport setting.BMJ global health · 2022Trial
- Scent dog identification of SARS-CoV-2 infections in different body fluids.BMC infectious diseases · 2021Trial
- Scent dog identification of samples from COVID-19 patients - a pilot study.BMC infectious diseases · 2020Trial
- The Role of Olfaction in Dogs: Evolution, Biology, and Human-Oriented Work.Animals : an open access journal from MDPI · 2026Review
- Innovative Approaches to Early Detection of Cancer-Transforming Screening for Breast, Lung, and Hard-to-Screen Cancers.Cancers · 2025Review
- Study of sampling phases for body odor sampling prior to analysis by TD-GC×GC/ToFMS.Analytical and bioanalytical chemistry · 2025Article
- Steps toward clinical validation of exhaled volatile organic compound biomarkers for hypoglycemia in persons with type 1 diabetes.Scientific reports · 2025Article
- Examination of Intermolecular Forces Influencing Headspace Analysis of Biological Samples.Metabolites · 2025Article
- Article
- Can dogs sniff out cancer? Exploring the role of medical detection dogs in Hong Kong's early diagnosis strategies.Frontiers in medicine · 2025Article
- Applications of Pythium- and Phytophthora-produced volatiles in plant disease control.Applied microbiology and biotechnology · 2024Review
- Development of an automated human scent olfactometer and its use to evaluate detection dog perception of human scent.PloS one · 2024Article
- Article
- The Olfaction Ability of Medical Detection Canine to Detect Prostate Cancer From Urine Samples: Progress Captured in Systematic Review and Meta-Analysis.World journal of oncology · 2023Article
- Interactions between Humans and Dogs during the COVID-19 Pandemic: Recent Updates and Future Perspectives.Animals : an open access journal from MDPI · 2023Review
- Is diagnostic performance of SARS-CoV-2 detection dogs reduced -due to virus variation- over the time?Applied animal behaviour science · 2023Article
- The Use of Biological Sensors and Instrumental Analysis to Discriminate COVID-19 Odor Signatures.Biosensors · 2022Article
- In search of COVID-19: The ability of biodetection canines to detect COVID-19 odours from clinical samples.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The volatilome is the entire set of volatile organic compounds (VOC) produced by an organism. The accumulation of VOC inside and outside of the body reflects the unique metabolic state of an organism. Scientists are developing technologies to non-invasively detect VOC for the purposes of medical diagnosis, therapeutic monitoring, disease outbreak containment, and disease prevention. Detection dogs are proven to be a valuable real-time mobile detection technology for the detection of VOC related to explosives, narcotics, humans, and many other targets of interests. Little is known about what dogs are detecting when searching for biological targets. It is important to understand where biological VOC originates and how dogs might be able to detect biological targets. This review paper discusses the recent scientific literature involving VOC analysis and postulates potential biological targets for canine detection. Dogs have shown their ability to detect pathogen and disease-specific VOC. Future research will determine if dogs can be employed operationally in hospitals, on borders, in underserved areas, on farms, and in other operational environments to give real-time feedback on the presence of a biological target.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.