Evidence map›Paper›PMID 27446928›Full record

ReviewFrontiers in molecular biosciences2016

Potential Roles of Adropin in Central Nervous System: Review of Current Literature.

Shima Shahjouei, Saeed Ansari, Tayebeh Pourmotabbed, Ramin Zand

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Adropin: A New Regulator of Testicular Function-What Do We Know So Far?International journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Review
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  7. Article
  8. Article
  9. Protective roles of adropin in neurological disease.American journal of physiology. Cell physiology · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Shima ShahjoueiDepartment of Neurosurgery, Tehran University of Medical Sciences Tehran, Iran.
Saeed AnsariDepartment of Neurology, University of Tennessee Health Science Center Memphis, TN, USA.
Tayebeh PourmotabbedDepartment of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center Memphis, TN, USA.
Ramin ZandDepartment of Neurology, University of Tennessee Health Science CenterMemphis, TN, USA; Biocomplexity Institute, Virginia Polytechnic Institute and State UniversityBlacksburg, VA, USA.
University of Tennessee Health Science Center · USTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adropin is a 4.9 kDa peptide that is important for maintenance of metabolic and non-metabolic homeostasis. It regulates glucose and fatty acid metabolism and is involved in endothelial cell function and endothelial nitric oxide (NO) synthase bioactivity as well as physical activity and motor coordination. Adropin is expressed in many tissues and organs including central nervous system (CNS). This peptide plays a crucial role in the development of various CNS disorders such as stroke, schizophrenia, bipolar disorder as well as Alzheimer's, Parkinson's, and Huntington's diseases. In this comprehensive review, the potential roles of adropin in cellular signaling pathways that lead to pathogenesis and/or treatment of CNS disorders will be discussed.

Indexed as

adropinbiomarkercellular signaling pathwaysneurodegenerative diseaseneuroprotectionpredictortherapeutic

Identifiers

PMID27446928
PMCPMC4921473
OpenAlexW2463584226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.