Evidence map›Paper›PMID 27446898›Full record

ArticleFrontiers in public health2016

Study Protocol on Hormonal Mediation of Exercise on Cognition, Stress and Immunity (PRO-HMECSI): Effects of Different Exercise Programmes in Institutionalized Elders.

Ana Maria Teixeira, José Pedro Ferreira, Eef Hogervorst, Margarida Ferreira Braga, Stephan Bandelow, Luís Rama, António Figueiredo, Maria João Campos, Guilherme Eustáquio Furtado, Matheus Uba Chupel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Ana Maria TeixeiraFaculty of Sport Sciences and Physical Education, University of Coimbra , Coimbra , Portugal.
José Pedro FerreiraFaculty of Sport Sciences and Physical Education, University of Coimbra , Coimbra , Portugal.
Eef HogervorstNational Centre for Sports and Exercise Medicine, Loughborough University , Loughborough , UK.
Margarida Ferreira BragaMedical Psychology Unit, Department of Clinical Neurosciences and Mental Health, Faculty of Medicine, Porto University , Porto , Portugal.
Stephan BandelowNational Centre for Sports and Exercise Medicine, Loughborough University , Loughborough , UK.
Luís RamaFaculty of Sport Sciences and Physical Education, University of Coimbra , Coimbra , Portugal.
António FigueiredoFaculty of Sport Sciences and Physical Education, University of Coimbra , Coimbra , Portugal.
Maria João CamposFaculty of Sport Sciences and Physical Education, University of Coimbra , Coimbra , Portugal.
Guilherme Eustáquio FurtadoFaculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal; CAPES Foundation, Ministry of Education, Brasilia, Brazil.
Matheus Uba ChupelFaculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal; CAPES Foundation, Ministry of Education, Brasilia, Brazil.
Filipa Martins PedrosaFaculty of Sport Sciences and Physical Education, University of Coimbra , Coimbra , Portugal.
University of Coimbra · PTLoughborough University · GBUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) in elders has been shown to have positive effects on a plethora of chronic diseases and to improve immunity, mental health, and cognition. Chronic stress has also been shown to have immuno-suppressive effects and to accelerate immunosenescence. Exercise could be a significant factor in ameliorating the deleterious effects of chronic stress, but variables such as the type, intensity, and frequency of exercise that should be performed in order to effectively reduce the stress burden need to be defined clearly. PRO-HMECSI will allow us to investigate which hormonal and immunological parameters are able to mediate the effects of exercise on mucosal immunity, psychological/biological stress, and cognitive functioning in older people. Phase I consists of an observational cross-sectional study that compares elders groups (n = 223, >65 years) by functional fitness levels aiming to identify biomarkers involved in maintaining immune and mental health. Neuroendocrine and immune biomarkers of stress, psychological well-being related to mental health, neurocognitive function, functional fitness, and daily PA will be evaluated. Phase II consists of a 28-week intervention in elders with mild cognitive impairment (MCI) profile (n = 149, >65 years, divided in three groups of exercise and one control group), aiming to investigate whether the positive effect of three different types of chair-based exercise programs on physical and psychological health is mediated by an optimal endocrine environment. Primary outcomes are measures of cognitive function and global health. Secondary outcomes include the evaluation the other dimensions such as immune function, psychological health, and depression. Few studies addressed the effects of different types of exercise interventions in older population samples with MCI. We will also be able to determine which type of exercise is more effective in the immune and hormonal function of this population.

Indexed as

cognitionexerciseimmunitymental healtholder women

Identifiers

PMID27446898
PMCPMC4921497
OpenAlexW2462295526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.