Trial reportCanadian journal of gastroenterology & hepatology2016
Split-Dose Polyethylene Glycol Is Superior to Single Dose for Colonoscopy Preparation: Results of a Randomized Controlled Trial.
Trial report in Canadian journal of gastroenterology & hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Prospective Trial Comparing Single Dose Polyethylene Glycol-based Lavage Versus Split Dose Polyethylene Glycol-based Lavage in the Preparation of Patients Undergoing Colonoscopy
Comparison of Bowel Preparation Using 2 Liter Polyethylene Glycol Regimen Plus Elobixibat Versus 4-Liter Polyethylene Glycol Regimen: a Randomized Controlled Trial
Who cites it
14 citing papers in PubMed.
- Low-residue diet with oral nutritional supplements prior to colonoscopy improves the quality of bowel preparation: an endoscopist-blinded, randomized controlled trial.BMC gastroenterology · 2025Trial
- Prospective, randomized study comparing two different regimens of split-dose polyethylene glycol and their effect on endoscopic outcomes.BMC gastroenterology · 2024Trial
- The efficacy and tolerability of sports drink versus water in bowel preparations: a randomised controlled study.Trials · 2022Trial
- Efficacy and Tolerability of Two Different Low-Volume Split-Dose Polyethylene Glycol Electrolytes Solution Bowel Preparation for Morning Colonoscopy.Canadian journal of gastroenterology & hepatology · 2022Trial
- Trial
- Pilot randomized trial of efficacy and safety of yogic technique versus polyethylene glycol solution for bowel preparation in colonoscopy.iGIE : innovation, investigation and insights · 2025Article
- Vitamin drinks improve palatability and reduce adverse events associated to polyethylene glycol electrolyte solutions.Heliyon · 2024Article
- Bowel preparation efficacy and safety of compound polyethylene glycol electrolyte powder combined with linaclotide for colonoscopy: A randomized controlled trial.JGH open : an open access journal of gastroenterology and hepatology · 2023Article
- Could atmospheric temperature impact on adequate colon cleansing for colonoscopy? An observational, single-institution study.International journal of colorectal disease · 2023Observational
- Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature.World journal of gastroenterology · 2023Review
- Novel frontiers of agents for bowel cleansing for colonoscopy.World journal of gastroenterology · 2021Review
- Bowel Preparation for Pediatric Colonoscopy.Frontiers in pediatrics · 2021Review
- Efficacy and Patient Tolerability of Split-Dose Sodium Picosulfate/Magnesium Citrate (SPMC) Oral Solution Compared to the Polyethylene Glycol (PEG) Solution for Bowel Preparation in Outpatient Colonoscopy: An Evidence-Based Review.Clinical and experimental gastroenterology · 2020Review
- Assessing Bowel Cleansing for Colonoscopy: Changing Our Focus to What Really Matters.Canadian journal of gastroenterology & hepatology · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. The efficacy of colonoscopy in detecting abnormalities within the colon is highly dependent on the adequacy of the bowel preparation. The objective of this study was to compare the efficacy, safety, and tolerability of PEG lavage and split-dose PEG lavage with specific emphasis on the cleanliness of the right colon. Methods. The study was a prospective, randomized, two-arm, controlled trial of 237 patients. Patients between the age of 50 and 75 years were referred to an outpatient university screening clinic for colonoscopy. Patients were allocated to receive either a single 4 L PEG lavage or a split-dose PEG lavage. Results. Overall, the bowel preparation was superior in the split-dose group compared with the single-dose group (mean Ottawa score 3.50 ± 2.89 versus 5.96 ± 3.53; P < 0.05) and resulted in less overall fluid in the colon. This effect was observed across all segments of the colon assessed. Conclusions. The current study supports use of a split-dose PEG lavage over a single large volume lavage for superior bowel cleanliness, which may improve polyp detection. This trial is registered with ClinicalTrials.gov identifier NCT01610856.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.