Evidence map›Paper›PMID 27446664›Full record

ArticleBiomedical optics express2016

Analyzing spatial correlations in tissue using angle-resolved low coherence interferometry measurements guided by co-located optical coherence tomography.

Sanghoon Kim, Stephanie Heflin, Laura A Kresty, Meredith Halling, Laura N Perez, Derek Ho, Michael Crose, William Brown, Sina Farsiu, Vadim Arshavsky and 1 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sanghoon KimDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Stephanie HeflinDepartment of Ophthalmology, Duke University, Durham, NC 27708, USA.
Laura A KrestyDepartment of Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226 USA.
Meredith HallingDepartment of Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226 USA.
Laura N PerezDepartment of Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226 USA.
Derek HoDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Michael CroseDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
William BrownDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Sina FarsiuDepartment of Ophthalmology, Duke University, Durham, NC 27708, USA.
Vadim ArshavskyDepartment of Ophthalmology, Duke University, Durham, NC 27708, USA.
Adam WaxDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
Novel Coherence Imaging to Evaluate the Health of the Cervical EpitheliumR01CA167421 · NCI · DUKE UNIVERSITY · PI WAX, ADAM · 2014 to 2018
$3.0M
Role of impaired protein degradation in photoreceptor degenerationR01EY022959 · NEI · DUKE UNIVERSITY · PI ARSHAVSKY, VADIM Y · 2013 to 2017
$2.2M
Inhibition of Reflux-Induced Esophageal Adenocarcinoma by ProanthocyanidinsR01CA158319 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRESTY, LAURA A · 2012 to 2016
$1.6M
Coherent light scattering for early detection of retinal diseaseR21EY023451 · NEI · DUKE UNIVERSITY · PI WAX, ADAM · 2013 to 2014
$417k
NCI NIH HHS R01 CA158319NCI NIH HHS R01 CA167421NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY022959NEI NIH HHS R21 EY023451
6 · The paper itself

Abstract

Angle-resolved low coherence interferometry (a/LCI) is an optical technique used to measure nuclear morphology in situ. However, a/LCI is not an imaging modality and can produce ambiguous results when the measurements are not properly oriented to the tissue architecture. Here we present a 2D a/LCI system which incorporates optical coherence tomography imaging to guide the measurements. System design and characterization are presented, along with example cases which demonstrate the utility of the combined measurements. In addition, future development and applications of this dual modality approach are discussed.

Indexed as

(120.3180) Interferometry(290.0290) Scattering(290.3200) Inverse scattering(290.5820) Scattering measurements

Identifiers

PMID27446664
PMCPMC4929650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.